Résumé :
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[BDSP. Notice produite par INIST-CNRS 2Fp9AR0x. Diffusion soumise à autorisation]. Aim : To investigate the development of blood pressure (BP) determinants over a period of 6 years in a birth cohort of middle-aged Swedish men. Methods : Men born 1953 and 1954 living in Helsingborg, Southern Sweden, were surveyed at 37,40 and 43 years of age. Baseline participation rate was 68% (n=991). S-Cholesterol, HDL-Cholesterol, systolic and diastolic blood pressure (SBP and DBP) and anthropomorphic measurements were collected and a questionnaire covering ethnicity, smoking, leisure time physical activity (LTPA) and alcohol consumption was completed. Results : At these surveys, SBP means were : 131,132,135 mm Hg and DBP were 83,83 and 85 mm Hg respectively. Body mass index (BMI), waist hip ratio (WHR), S-Cholesterol and alcohol consumption consistently showed cross-sectional positive associations with SBP and DBP. One mmol/L higher S-Cholesterol at baseline predicted an increase in SBP by 1.16 mm Hg (confidence interval, CI : 0.25 ; 2.07) over 6 years. At age 40, there was a 4.4 mm Hg (p<0.020) difference in SBP and a 2.64 mm Hg (p<0.056) difference in DBP means between the low and high alcohol consumption. Corresponding differences at age 43 were SBP 5.28 mm Hg (p<0.023) and DBP 5.4 mm Hg (p<0.000). Men born in Sweden had a higher baseline SBP (delta=4 mm Hg, CI : 2.11 ; 6.35) and showed a higher 6 year increase in SBP (2.80 mm Hg CI : 0.07 ; 5.53) than men born abroad. Conclusions : Body composition, ethnicity and alcohol consumption are strong determinants for the development of BP. These findings have to be considered in strategies for primary prevention of hypertension in younger middle-aged men.
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