| Titre : | A newly identified tick-borne Borrelia species and relapsing fever in Tanzania. (2003) |
| Auteurs : | KISINZA (William-N) : TZA. National Institute For Medical Research. Dar es Salaam. ; Masahito FUKUNAGA ; P.J. MCCALL ; Harumi MITANI ; TALBERT (Alison) : TZA. Mvuml Hospital. Dodoma. ; Laboratory of Molecular Microbiology. Faculty of Pharmacy and Pharmaceutical Sciences. Fukuyama University. Fukuyama Hiroshima. JPN ; Vector Research Group. Liverpool School of Tropical Medicine. Liverpool. GBR |
| Type de document : | Article |
| Dans : | Lancet (The) (vol. 362, n° 9392, 2003) |
| Pagination : | 1283-1284 |
| Langues: | Anglais |
| Mots-clés : | Bactérie ; Bactériose ; Infection ; Tanzanie ; Afrique ; Enfant ; Homme ; Epidémiologie ; Endémie |
| Résumé : | [BDSP. Notice produite par INIST-CNRS 8FR0x4dk. Diffusion soumise à autorisation]. Tick-borne relapsing fever caused by the spirochaete Borrelia duttonii is a common cause of serious illness in central Tanzania. Screening of Ornithodoros sp. ticks from infested houses for the presence of B duttonii had detected a previously unidentified species of Borrelia. We investigated whether this species infected the human population in a central Tanzanian village, by use of blood slide examination and PCR. PCR was twice as sensitive in detection of infections, showing Borrelia sp. in six (11%) of 54 children with fever, and in 13 (4%) of 307 otherwise healthy children. Genotyping Borrelia from 17 infections identified Borrelia duttonii and an unnamed species. Our findings show that the newly discovered species is a causal agent of tick-borne relapsing fever. |
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