| Titre : | Serological survey of immunity to tetanus in adult population of Northern Halkidiki, Greece. (2003) |
| Auteurs : | Nikolaos SYMEONIDIS ; Antonios ANTONIADIS ; Efterni DIZA ; Eudoxia HOUIAZI ; Efimia SOULIOU ; Chrysanthos SYMEONIDIS ; Athanassios SYMEONIDIS ; Aristotelian University of Thessaloniki. Medical School. Laboratory of Microbiology. GRC ; Paleohori Health Center. Gmh. Halkidiki. GRC |
| Type de document : | Article |
| Dans : | European journal of epidemiology (vol. 18, n° 12, 2003) |
| Pagination : | 1147-1152 |
| Langues: | Anglais |
| Mots-clés : | Vaccination ; Vaccin antitétanique ; Tétanos ; Bactériose ; Infection ; Sérologie ; Homme ; Grèce ; Europe ; Prévention santé |
| Résumé : | [BDSP. Notice produite par INIST-CNRS 5pR0xGd6. Diffusion soumise à autorisation]. Background : Despite the implementation of the obligatory anti-tetanus vaccination, the tetanus cases in Greece are not eliminated. Because of the increased possibility of Clostridium tetani infection of the Northern Halkidiki population - like any other rural population - the evaluation of the immunity to tetanus in the area is considered necessary. Methods : The tetanus antitoxin levels were determined using the enzyme-linked immunosorbent assay (ELISA) in 405 healthy adult individuals attending the health center for routine laboratory tests. Results : 64.4% of the studied population was found protected (tetanus antitoxin levels>=0.1 IU/ml). The percentage of protected people decreased as age increased from 83.3% in the 21-30 to 51.2% in the>60 age group. 82.1% of the tested males and 52.6% of the tested females had tetanus antitoxin levels>=0.1 IU/ml (p<0.0001). The percentages of immune men (100-66.2% in various age groups) were found higher than those of women (80.8-35.5% in the respective age groups). The geometrical mean titres (GMTs) were 0.44 in all of 261 immune people, 0.53 in 133 immune men and 0.37 in 128 immune women (p=0.0021). Conclusion : The proportion of protection among men over 60 and women over 30 years old is inadequate, the levels of tetanus antitoxin decline with age and a significant difference was found between the proportion of protection of males and females. |
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