| Titre : | Condom effectiveness for reducing transmission of gonorrhea and chlamydia : The importance of assessing partner infection status. (2004) |
| Auteurs : | Lee WARNER ; Harland-D AUSTIN ; Gail BOLAN ; John-Mjr DOUGLAS ; Martin FISHBEIN ; Mary-L KAMB ; David-G KLEINBAUM ; Maurizio MACALUSO ; Ckevin MALOTTE ; Daniel-R NEWMAN ; Thomas-A PETERMAN ; Judy ROGERS ; Jonathan-M ZENILMAN ; Centers for Disease Control and Prevention. Division of Hiv Aids Prevention. National Center for Hiv Std and Tb Prevention. Atlanta. GA. USA ; Project Respect Study Group. INC ; Rollins School of Public Health of Emory University. Department of Epidemiology. Atlanta. GA. USA |
| Type de document : | Article |
| Dans : | American journal of epidemiology (vol. 159, n° 3, 2004) |
| Pagination : | 242-251 |
| Langues: | Anglais |
| Mots-clés : | Gonococcie ; Bactériose ; Infection ; Préservatif ; Comportement sexuel ; Bactérie ; Chlamydia ; Microbiologie ; Chlamydiose ; Homme ; Efficacité ; Evaluation ; Maladie sexuellement transmissible |
| Résumé : | [BDSP. Notice produite par INIST-CNRS xm27LR0x. Diffusion soumise à autorisation]. This analysis examined the importance of differential exposure to infected partners in epidemiologic studies of latex condom effectiveness for prevention of sexually transmitted infections. Cross-sectional, enrollment visit data were analyzed from Project RESPECT, a trial of counseling interventions conducted at five publicly funded US sexually transmitted disease clinics between 1993 and 1997. The association between consistent condom use in the previous 3 months and prevalent gonorrhea and chlamydia (Gc/Ct) was compared between participants known to have infected partners and participants whose partner infection status was unknown. Among 429 participants with known Gc/Ct exposure, consistent condom use was associated with a significant reduction in prevalent gonorrhea and chlamydia (30% vs. 43% ; adjusted prevalence odds ratio=0.42,95% confidence interval : 0.18,0.99). Among 4,314 participants with unknown Gc/Ct exposure, consistent condom use was associated with a lower reduction in prevalent gonorrhea and chlamydia (24% vs. 25% ; adjusted prevalence odds ratio=0.82,95% confidence interval : 0.66,1.01). The number of unprotected sex acts was significantly associated with infection when exposure was known (p for trend<0.01) but not when exposure was unknown (p for trend=0.73). Restricting analyses to participants with known exposure to infected partners provides a feasible and efficient mechanism for reducing confounding from differential exposure to infected partners in condom effectiveness studies. |
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