| Titre : | Racial differences in survival among men with prostate cancer and comorbidity at time of diagnosis. (2004) |
| Auteurs : | Vincent-L FREEMAN ; Ramon DURAZO-ARVIZU ; Marc-P JOHNSON ; Lashon-C KEYS ; Vikas-K PATEL ; Kristian SCHAFERNAK ; Loyola University Stritch School of Medicine. Department of Medicine. Maywood. IL. USA |
| Type de document : | Article |
| Dans : | American journal of public health (vol. 94, n° 5, 2004) |
| Pagination : | 803-808 |
| Langues: | Anglais |
| Mots-clés : | Race ; Survie ; Homme ; Maladie associée ; Temps ; Diagnostic ; Cancer ; Prostate ; Etat santé ; Appareil urinaire [pathologie] |
| Résumé : | [BDSP. Notice produite par INIST-CNRS PR0xKjM5. Diffusion soumise à autorisation]. Objectives : This study evaluated the effect of comorbidity at diagnosis on racial differences in survival among men with prostate cancer. Methods : Clinical and demographic data were abstracted from records of 864 patients diagnosed at 4 Chicago area hospitals between 1986 and 1990. Comorbidity was scored on the basis of clinical information in the Charlson index. Cause-specific relative mortality adjusted for age, stage, differentiation, and treatment was compared across Charlson scores with Cox proportional hazards functions. Results : Blacks had significantly greater mortality from prostate cancer and other causes (vs Whites, relative risk [95% confidence interval]=1.84 [1.22,2.791 and 1.69 [1.33,2.29], respectively ; P<. 001). However, differences disappeared as initial comorbidity increased (1.75 [1.33,2.31] vs 0.90 [0.59,1.29] for scores=0 and>=5, respectively). Conclusions : Absence of a significant preexisting medical diagnosis is associated with a higher risk for excess mortality among Black men diagnosed with prostate cancer. |
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