| Titre : | Antidepressant medication use and non-Hodgkin's lymphoma risk : No association. (2004) |
| Auteurs : | Saira BAHL ; Michelle COTTERCHIO ; Neil KLAR ; KREIGER (Nancy) : CAN. Department of Nutritional Sciences. University of Toronto. Toronto. ON. ; Cancer Care Ontario. Division of Preventive Oncology. Toronto. ON. CAN |
| Type de document : | Article |
| Dans : | American journal of epidemiology (vol. 160, n° 6, 2004) |
| Pagination : | 566-575 |
| Langues: | Anglais |
| Mots-clés : | Antidépresseur ; Cancer ; Facteur risque ; Homme ; Facteur associé ; Association ; Enquête cas témoin ; Epidémiologie ; Médicament psychotrope |
| Résumé : | [BDSP. Notice produite par INIST-CNRS 6R0xhlKU. Diffusion soumise à autorisation]. Animal and human studies have suggested that antidepressant medications may be associated with several cancers. The authors evaluated the association between antidepressant medication use and the risk of non-Hodgkin's lymphoma using a Canadian population-based case-control study, the National Enhanced Cancer Surveillance Study. Non-Hodgkin's lymphoma cases (n=638) diagnosed in 1995-1996 were identified using the Ontario Cancer Registry, and controls (n=1,930) were identified from the Ontario Ministry of Finance Property Assessment Database. Antidepressant medication use was ascertained using a self-administered questionnaire. Multivariate logistic regression was used to estimate odds ratios. "Ever" use of antidepressant medications was not associated with non-Hodgkin's lymphoma risk. The odds ratio for non-Hodgkin's lymphoma with 25 or more months of tricyclic antidepressant medication use was 1.6 ; however, this was nonsignificant. Duration or history of use or individual types of antidepressant medications were not associated with non-Hodgkin's lymphoma risk. These findings do not support an increased risk of non-Hodgkin's lymphoma with antidepressant medication use. |
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