Titre :
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Socioeconomic status and risk for arsenic-related skin lesions in Bangladesh. (2007)
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Auteurs :
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Maria ARGOS ;
AHSAN (Habibul) : USA. Herbert Irving Comprehensive Cancer Center. Columbia University. New York. ;
GRAZIANO (Joseph-H) : USA. College of Physicians and Surgeons. Columbia University. New York. ;
Geoffrey-R HOWE ;
A.Z.M. IFTIKHAR HUSSAIN ;
Hassina MOMOTAJ ;
Faruque PARVEZ ;
. YU CHEN ;
Columbia University. Mailman School of Public Health. Department of Environmental Health Sciences. New York. USA
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Type de document :
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Article
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Dans :
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American journal of public health (vol. 97, n° 5, 2007)
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Pagination :
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825-831
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Langues:
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Anglais
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Mots-clés :
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Peau [pathologie]
;
Facteur socioéconomique
;
Facteur risque
;
Risque
;
Arsenic
;
Bengla Desh
;
Asie
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Résumé :
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[BDSP. Notice produite par INIST-CNRS uatVR0xk. Diffusion soumise à autorisation]. Objectives. Arsenic contamination of groundwater is a severe public health crisis in Bangladesh, where the population is exposed to arsenic in drinking water through tube wells used for groundwater collection. In this study, we explored the association between socioeconomic status and arsenic toxicity. Methods. We used baseline data from 11 438 men and women who were recruited into the Health Effects of Arsenic Longitudinal Study (HEALS), a prospective cohort study on the health effects of arsenic exposure in Bangladesh. We conducted analyses with logistic regression and generalized estimating equations. Results. We found a strong dose-response association with all measures of arsenic exposure and skin lesions. We also found that the effect of arsenic was modified by land ownership on a multiplicative scale, with an increased risk among non-land owners associated with well water arsenic (P=04) and urinary total arsenic concentrations (P=03). Conclusions. Our study provides insight into potentially modifiable host characteristics and identifies factors that may effectively target susceptible population subgroups for appropriate interventions.
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