| Titre : | Are childhood socio-economic circumstances related to coronary heart disease risk ? Findings from a population-based study of older men. Commentary. (2007) |
| Auteurs : | Sheena-E RWNSAY ; GLYMOUR (Mmaria) / disc. : USA. Department of Epidemiology. Mailman School of Public Health at Columbia University. New York. NY. ; Lucy-T LENNON ; Richard-W MORRIS ; S.G. WANNWNETHEE ; WHINCUP (Peter-H) : GBR. Department of Community Health Sciences. St George's University of London. London. ; Department of Primary Care and Population Sciences. Royal Free Hospital and University College Medical School. London. GBR |
| Type de document : | Article |
| Dans : | International journal of epidemiology (vol. 36, n° 3, 2007) |
| Pagination : | 560-568 |
| Langues: | Anglais |
| Mots-clés : | Cardiopathie coronaire ; Facteur risque ; Epidémiologie ; Facteur socioéconomique ; Royaume Uni ; Adulte ; Europe ; Homme ; Appareil circulatoire [pathologie] |
| Résumé : | [BDSP. Notice produite par INIST-CNRS 6EoR0xG6. Diffusion soumise à autorisation]. Background The independent influence of childhood social circumstances on health in later life remains uncertain. We examined the extent to which childhood socio-economic circumstances are related to the risk of coronary heart disease (CHD) in older British men, taking account of adult social class and behavioural risk factors. Methods A socio-economically representative sample of 5552 British men (52-74 years) with retrospective assessment of childhood socio-economic circumstances (father's occupation and childhood household amenities) who were followed up for CHD (fatal and non-fatal) for 12 years. Results Men whose childhood social class was manual had an increased hazard ratio (HR) 1.34 (95% CI 1.11-1.63) - this effect was diminished when adjusted for adult social class and adult behavioural risk factors (cigarette smoking, alcohol, physical activity and body weight) (HR 1.19 ; 95% CI 0.97-1.46). Men whose family did not own a car in their childhood were at increased CHD risk even after adjustments for adult social class and behaviours (HR 1.35,95% CI 1.04-1.75). Men with combined exposure to both childhood and adult manual social class had the highest risk of CHD (HR 1.51 ; 95% CI 1.19-1.91) ; this was substantially reduced by adjustment for adult behavioural risk factors (adjusted HR 1.28 ; 95% CI 0.99-1.65). Conclusions Less affluent socio-economic conditions in childhood may have a modest persisting influence on risk of CHD in later life. |

