| Titre : | Broader vaccination of expatriates against HBV infection : do we reach those at highest risk ? (1999) |
| Auteurs : | W. GOETTSCH ; R. DE GRAAF ; J.W. DORIGO-ZETSMA ; H. HOUWELING ; G. VAN ZESSEN ; National Institute of Public Health and the Environment. Bilthoven. NLD ; Netherlands Institute of Mental Health and Addiction. Utrecht. NLD |
| Type de document : | Article |
| Dans : | International journal of epidemiology (vol. 28, n° 6, 1999) |
| Pagination : | 1161-1166 |
| Langues: | Anglais |
| Mots-clés : | Hépatite virale B ; Virose ; Infection ; Homme ; Prévention santé ; Vaccination ; Questionnaire ; Résultat ; Examen sérologique ; Anticorps ; Facteur risque ; Comportement sexuel ; Prise de risque ; Exposition professionnelle ; Europe ; Appareil digestif [pathologie] ; Foie [pathologie] ; Pays Bas |
| Résumé : | [BDSP. Notice produite par INIST u4R0x4oq. Diffusion soumise à autorisation]. Background The effects of the implementation of a new Dutch hepatitis B virus (HBV) vaccination strategy (1991) for expatriates on HBV vaccination status and HBV infection prevalence were evaluated in a group of 864 expatriates returning from HBV-endemic areas. Methods During a routine medical examination at the participating medical centres Dutch expatriates were asked to complete a questionnaire and to donate a serum sample for HBV testing. Blood was tested for antibodies against the hepatitis B core (anti-HBc) and surface antigens (anti-HBs), The serological data were related to information gathered on aspects of residence, sexual risk behaviour and occupational risks. Results A significantly higher percentage of expatriates (37%) were vaccinated compared to a previous study in 1987-1989 (14%). However, the percentage of expatriates with HBV infection markers (5%) had not decreased significantly. Moreover, the risk for HBV infection, as determined with a questionnaire, was still affected by well-known risk factors such as homosexual contacts (odds ratio [OR]=6.6,95% CI 1.7-26), more than five casual local partners (OR=3.6,95% CI 1.2-11) and more than five occupational accidents in the last 3 years (OR=20,95% CI : 2-187). Detailed analysis of the vaccination status indicated that especially young female expatriates with low risk behaviour (65%) were protected, while older male expatriates with high risk behaviour were less protected (20%). (...) |
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