| Titre : | Long-term survival after infection with human immunodeficiency virus type 1 (HIV-1) among homosexual men in hepatitis B vaccine trial cohorts in Amsterdam, New York City, and San Francisco, 1978-1995. (1999) |
| Auteurs : | B.A. KOBLIN ; S.P. BUCHBINDER ; R.A. COUTINHO ; LEIGH REN . (.) ; C.E. STEVENS ; B.H.B. VAN BENTHEM ; G.J.P. VAN GRIENSVEN ; E. VITTINGHOFF ; Aids Office. Department of Public Health. San Francisco. CA. USA ; Municipal Health Service. Department of Public Health. Amsterdam. NLD ; The Wolf Szmuness Laboratory of Epidemiology. The New York Blood Center. New York. NY. USA |
| Type de document : | Article |
| Dans : | American journal of epidemiology (vol. 150, n° 10, 1999) |
| Pagination : | 1026-1030 |
| Langues: | Anglais |
| Mots-clés : | Sida ; Virose ; Infection ; VIH ; Rétrovirus ; Virus ; Hépatite virale B ; Homosexualité ; Epidémiologie ; Survie ; Long terme ; Pronostic ; Homme ; Immunopathologie ; Appareil digestif [pathologie] ; Foie [pathologie] |
| Résumé : | [BDSP. Notice produite par INIST sR0xR8yl. Diffusion soumise à autorisation]. Information on long-term survival after infection with human immunodeficiency virus type 1 (HIV-1) is limited. In hepatitis B vaccine trials in Amsterdam, New York City, and San Francisco, 362 gay men were followed up to 18 years (1978-1995). The median survival time from seroconversion was 12.1 years (95% confidence interval : 11.4,12.9). The annual risk of dying increased at a constant rate until 8 years after seroconversion and then leveled off, suggesting a group that is relatively resistant to progression. These data provide a picture of the natural history of HIV-1 infection, especially in the era prior to widespread use of highly effective treatments. |
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