| Titre : | East Ireland 1980-1994 : epidemiology of neural tube defects. (1999) |
| Auteurs : | R.J. MCDONNELL ; P. DACK ; V. DELANEY ; Z. JOHNSON ; Health Information Unit. Eastern Health Board. Dr Steeven's Hospital. Dublin. IRL |
| Type de document : | Article |
| Dans : | Journal of epidemiology and community health (vol. 53, n° 12, 1999) |
| Pagination : | 782-788 |
| Langues: | Anglais |
| Mots-clés : | Malformation tube neural ; Malformation ; Maladie congénitale ; Registre ; Epidémiologie ; Incidence ; Evolution ; Nouveau né ; Homme ; Irlande ; Europe |
| Résumé : | [BDSP. Notice produite par INIST 6s81R0x3. Diffusion soumise à autorisation]. Study objective-The objective of the study was to describe the epidemiology of neural tube defects (NTD) in the eastern region of Ireland using the EUROCAT register of congenital malformations. Design, setting and patients-EUROCAT registries monitor the prevalence of congenital anomalies in defined populations using multiple sources for case ascertainment. All cases of NTD on the Dublin EUROCAT register born between 1980 and 1994 were extracted and analysed. The crude birth prevalence rate for all NTD, spina bifida, anencephaly and encephalocoele were calculated for each year. Parameters measured were : sex ratio, stillbirth rate, proportion of low birth-weight babies (<2500 g) and the proportion who were premature (<37 weeks gestation). Main results-Of 821 NTD cases, 419 (51.0%) had spina bifida, 322 (39.2%) had anencephaly, 69 (8.4%) had encephalocoele and 11 (1.3%) were iniencephalic. The crude birth prevalence of NTD decreased fourfold from 46.9/10 000 births in 1980 to 11.6110 000 in 1994. The downward trend ceased during the early 1990s. Younger mothers had significantly higher rates of NTD affected births. Twenty two per cent of NTD cases had additional non-central nervous system anomalies. In 40 cases, there was a previous family history of NTD in siblings. Seasonal effects in birth prevalence were observed. Birth notification was the most frequent mechanism of ascertainment. (...) |
Service Documentation EHESP
Me connecter
PORTAIL DOCUMENTAIRE
École des hautes études en santé publique
Catalogue
Multi-bases
Accueil
Sélection de la langue
Adresse
Service Documentation EHESPBibliothèque Rennes Avenue du Professeur Léon Bernard – CS 74312 – 35043 Rennes Cedex Bibliothèque MSSH Paris 20 avenue George Sand - 93210 La Plaine Saint-Denis
France
Bibliothèque Rennes : 02 99 02 29 50 Bibliothèque MSSH Paris : 02 99 02 24 50
contact