| Titre : | Dietary fiber, weight gain, and cardiovascular disease risk factors in young adults. (1999) |
| Auteurs : | D.S. LUDWIG ; J.E. HILNER ; Drjr JACOBS ; C.H. KROENKE ; M.A. Pereira ; M.L. SLATTERY ; L. VAN HORN ; Division of Endocrinology. Department of Medicine. Children's Hospital. Boston. MA. USA ; Division of Epidemiology. School of Public Health. University of Minnesota. Minneapolis. USA |
| Type de document : | Article |
| Dans : | JAMA - Journal of the american medical association (vol. 282, n° 16, 1999) |
| Pagination : | 1539-1546 |
| Langues: | Anglais |
| Mots-clés : | Appareil circulatoire [pathologie] ; Facteur risque ; Etude comparée ; Consommation alimentaire ; Fibre alimentaire ; Prise poids ; Insuline ; Plasma sanguin ; Etats Unis ; Amérique ; Adulte ; Homme ; Amérique du Nord |
| Résumé : | [BDSP. Notice produite par INIST 9oNBR0xH. Diffusion soumise à autorisation]. Context Dietary composition may affect insulin secretion, and high insulin levels, in turn, may increase the risk for cardiovascular disease (CVD). Objective To examine the role of fiber consumption and its association with insulin levels, weight gain, and other CVD risk factors compared with other major dietary components. Design and Setting The Coronary Artery Risk Development in Young Adults (CARDIA) Study, a multicenter population-based cohort study of the change in CVD risk factors over 10 years (1985-1986 to 1995-1996) in Birmingham, Ala ; Chicago, III ; Minneapolis, Minn ; and Oakland, Calif. Participants A total of 2909 healthy black and white adults, 18 to 30 years of age at enrollment. Main Outcome Measures Body weight, insulin levels, and other CVD risk factors at year 10, adjusted for baseline values. Results After adjustment for potential confounding factors, dietary fiber showed linear associations from lowest to highest quintiles of intake with the following : body weight (whites : 174.8-166.7 lb [78.3-75.0 kg], P<. 001 ; blacks : 185.6-177.6 lb [83.5-79.9 kg], P=001), waist-to-hip ratio (whites : 0.813-0.801, P=004 ; blacks : 0.809-0.799, P=05), fasting insulin adjusted for body mass index (whites ; 77.8-72.2 pmol/L[11.2-10.4 muU/mL], P=007 ; blacks : 92.4-82.6 pmol/L [13.3-11.9 muU/mL], P=01) and 2-hour postglucose insulin adjusted for body mass index (whites : 261.1-234.7 pmol/L [37.6-33.8 muU/mL], P=03 ; blacks : 370.2-259.7 pmol/L [53.3-37. (...) |
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