Résumé :
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[BDSP. Notice produite par INIST 1MsF4R0x. Diffusion soumise à autorisation]. Context Obesity is a major health problem in the United States, but the number of obesity-attributable deaths has not been rigorously estimated. Objective To estimate the number of deaths, annually, attributable to obesity among US adults. Design Data from 5 prospective cohort studies (the Alameda Community Health Study, the Framingham Heart Study, the Tecumseh Community Health Study, the American Cancer Society Cancer Prevention Study I, and the National Health and Nutrition Examination Survey I Epidemiologic Follow-up Study) and 1 published study (the Nurses'Health Study) in conjunction with 1991 national statistics on body mass index distributions, population size, and overall deaths. Subjects Adults, 18 years or older in 1991, classified by body mass index (kg/m2) as overweight (25-30), obese (30-35), and severely obese (>35). Main Outcome Measure Relative hazard ratio (HR) of death for obese or overweight persons. Results The estimated number of annual deaths attributable to obesity varied with the cohort used to calculate the HRs, but findings were consistent overall. More than 80% of the estimated obesity-attributable deaths occurred among individuals with a body mass index of more than 30 kg/m2. When HRs were estimated for all eligible subjects from all 6 studies, the mean estimate of deaths attributable to obesity in the United States was 280 184 (range, 236 111-341 153). Hazard ratios also were calculated from data for nonsmokers or never-smokers only. (...)
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