Résumé :
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[BDSP. Notice produite par INIST-CNRS S8R0xtnj. Diffusion soumise à autorisation]. Context Each year in Thailand, about 10000 children are born at risk for mother-to-child human immunodeficiency virus (HIV) transmission. In 2000, Thailand implemented a national program to prevent mother-to-child HIV transmission. Objective To describe the results of implementation of the program. Design Monthly collection of summary data from hospitals. Setting Public health hospitals (n=822) in all 12 regions of Thailand, representing 75 provinces, excluding Bangkok. Participants Women giving birth from October 2000 through September 2001, including HIV-seropositive women and their neonates. Main Outcome Measures Percentages of women giving birth who were tested for HIV, HIV-seropositive women giving birth who received antenatal prophylactic antiretroviral drugs, and HIV-exposed neonates who received prophylactic antiretroviral drugs and infant formula. Results Among 573 655 women (range, 27344-77806 by region) giving birth, 554 912 (96.7%) received antenatal care (range, 91.9% 98.8% by region). Of 554912 women giving birth who had antenatal care, 517488 (93.3%) were tested for HIV (range, 87.7% - 99.4% by region) before giving birth ; of 18743 women giving birth who did not have antenatal care, 13314 (71.0%) were tested for HIV (range, 21.7% - 92.9% by region). Of 6646 HIV-seropositive women giving birth, 4659 (70.1%) received prophylactic antiretroviral drugs before delivery (range, 55.3% - 81.2% by region). Of 6475 neonates of HIV-seropositive women, 5741 (88.7%) received prophylactic antiretroviral drugs (range, 67.4% - 96.9% by region) and 5386 (83.2%) received infant formula (range, 65.3% - 100% by region). Conclusions Major program components of Thailand's national program for preventing mother-to-child HIV transmission were implemented. Thailand's experience may encourage other developing countries to implement or expand similar national programs.
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