Titre :
|
Estimation of the indirect effect of Haemophilus influenzae type b conjugate vaccine in an American Indian population. (2000)
|
Auteurs :
|
L.H. MOULTON ;
S.E. CHUNG ;
J. CROLL ;
R. REID ;
M. SANTOSHAM ;
R.C. WEATHERHOLTZ ;
Center for American Indian and Alaskan Native Health. Department of International Health. Baltimore. MD. USA
|
Type de document :
|
Article
|
Dans :
|
International journal of epidemiology (vol. 29, n° 4, 2000)
|
Pagination :
|
753-756
|
Langues:
|
Anglais
|
Mots-clés :
|
Vaccination
;
Bactérie
;
Programme élargi vaccination
;
Programme santé
;
Epidémiologie
;
Evaluation
;
Homme
;
Etats Unis
;
Amérique
;
Amérique du Nord
|
Résumé :
|
[BDSP. Notice produite par INIST LfTI7R0x. Diffusion soumise à autorisation]. Oropharyngeal carriage studies of Haemophilus influenzae type b (Hib) and the rapid drop in Hib invasive disease in countries with widespread Hib conjugate vaccine immunization programmes for infants have indicated there may be significant indirect effects (herd immunity) associated with these vaccines. Our goal was to quantify the magnitude of these effects in an American Indian population during its early years of Hib immunization, In a synthetic case-cohort study, we combined data from an efficacy trial, an immunization uptake records survey, and ongoing surveillance for Hib disease on the Navajo Nation from 1988 to 1992. Decline in the incidence of invasive Hib disease among children
|