| Titre : | Glucose intolerance and physical inactivity : The relative importance of low habitual energy expenditure and cardiorespiratory fitness. (2000) |
| Auteurs : | N.J. WAREHAM ; N.E. DAY ; M.Y. WONG ; Department of Community Medicine. Institute of Public Health. University of Cambridge. Cambridge. GBR |
| Type de document : | Article |
| Dans : | American journal of epidemiology (vol. 152, n° 2, 2000) |
| Pagination : | 132-139 |
| Langues: | Anglais |
| Mots-clés : | Diabète ; Activité physique ; Epidémiologie ; Facteur risque ; Prévention santé ; Homme ; Royaume Uni ; Europe ; Glande endocrine [pathologie] |
| Résumé : | [BDSP. Notice produite par INIST 4R0xSMBp. Diffusion soumise à autorisation]. Glucose intolerance and diabetes mellitus are associated with physical inactivity, but it is unclear whether preventive interventions should aim at increasing overall energy expenditure or increasing participation in vigorous, fitness-enhancing activities. Studies aimed at separating and quantifying the effects of these two dimensions of physical activity should use well-validated measurement instruments and employ a study design in which the bivariate error structure of these instruments is determined. In the Isle of Ely Study (Cambridgeshire, United Kingdom), 775 individuals aged 45-70 years in 1994-1997 completed a glucose tolerance test and assessment of 4-day physical activity level (total energy expenditure/basal metabolic rate) by heart rate monitoring, a technique that has been validated against doubly labeled water and whole-body calorimetry. Cardiorespiratory fitness (maximum oxygen uptake (VO2max) per kg)) was measured in a submaximal test. To correct for measurement error, the authors had 190 individuals repeat both tests on three occasions at 4-month intervals. Two-hour glucose level was negatively correlated with physical activity level (men : r=-0.22, p<0.001 ; women : r=-0.11, p<0.05) and VO2max per kg (men : r=-0.18, p<0.01 ; women : r=-0.19, p<0.001) and was positively correlated with age and obesity. (...) |
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