| Titre : | Reliability of self-reported diagnostic radiation history in BRCA1/2 mutation carriers. (2010) |
| Auteurs : | Anouk PIJPE ; . HEBON ; MANDERS (Peggy) : NLD. Department of Human Genetics. Radboud University Nijmegen Medical Center. Nijmegen. ; MULDER (Renée-L) : NLD. Department of Pediatric Oncology. Emma Children's Hospital. Academic Medical Center. Amsterdam. ; Matti-A ROOKUS ; Flora-E VAN LEEUWEN ; Department of Epidemiology. Netherlands Cancer Institute. Amsterdam. NLD |
| Type de document : | Article |
| Dans : | European journal of epidemiology (vol. 25, n° 2, 2010) |
| Pagination : | 103-113 |
| Langues: | Anglais |
| Mots-clés : | Cancer ; Fiabilité ; Autoquestionnaire ; Autoévaluation ; Diagnostic ; Rayonnement ; Histoire ; Historique ; Porteur ; Questionnaire ; Sein ; Homme ; Epidémiologie |
| Résumé : | [BDSP. Notice produite par INIST-CNRS 9j97lR0x. Diffusion soumise à autorisation]. We assessed reliability of self-reported diagnostic radiation history in BRCA1/2 mutation carriers with and without breast cancer. Within the frame-work of the HEBON study, 401 BRCA1/2 mutation carriers completed a baseline (1999-2004) and a follow-up questionnaire (2006-2007). Test-retest reliability of self-reported exposure to chest X-rays, fluoroscopies and mammograms was assessed for the entire study population and by case status. Overall proportion agreement on reporting ever/never exposure was good (>75%), while the corresponding kappa coefficients were between 0.40 and 0.75, indicating at least moderate reliability beyond chance. Reliability of number of exposures was also good (>75%). Proportion agreement on reporting age at first mammogram was low (40%) for exact consistency and moderate (60%) for consistency+/-1 year. Reliability of age at first mammogram was higher for cases than for unaffected carriers (P<0.001) but this difference disappeared when excluding diagnostic mammograms (P=0.60). In unaffected carriers proportion agreement on age at last mammogram was 50%. In general, the direction of disagreement on all items was equally distributed. More consistent reporting was mainly determined by a younger age at questionnaire completion. In conclusion, inconsistent self-report of diagnostic radiation by BRCA1/2 mutation carriers was mainly non-differential by disease status. |
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