| Titre : | In search of power and significance : issues in the design and analysis of stochastic cost-effectiveness studies in health care. (1994) |
| Auteurs : | B. O'BRIEN ; M.F. DRUMMOND ; et al. |
| Type de document : | Article |
| Dans : | Medical care (vol. 32, n° 2, 1994/02) |
| Pagination : | 150-163 |
| Langues: | Anglais |
| Mots-clés : | Analyse coût efficacité ; Economie santé ; Coût santé ; Méthodologie ; Etats Unis |
| Résumé : | Application of techniques such as cost-effectiveness analysis (CEA) is growing rapidly in health care. There are two general approaches to analysis : deterministic models based upon assuptions and secondary analysis of retrospective data, and prospective stochastic analyses in which the design of a clinical experiment such as randomised controlled trial is adapted to collect patient-specific data on costs and effects. An important methodological difference between these two approaches is in the quantification and analysis of uncertainty... We show how relevant variances can be estimated for this task and discuss the implications for the design and analysis of prospective economic studies. (résumé d'auteur). |
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