| Titre : | The association of modernization with dyslipidaemia and changes in lipid levels in the Polynesian population of Western Samoa. (1997) |
| Auteurs : | A.M. HODGE ; V.R. COLLINS ; G.K. DOWSE ; P. TOELUPE ; P.Z. ZIMMET ; International Diabetes Institute. Caulfield Victoria. AUS |
| Type de document : | Article |
| Dans : | International journal of epidemiology (vol. 26, n° 2, 1997) |
| Pagination : | 297-306 |
| Langues: | Anglais |
| Mots-clés : | Lipide ; Condition vie ; Epidémiologie ; Facteur risque ; Prévalence ; Homme ; Polynésie ; Océanie ; Métabolisme [pathologie] |
| Résumé : | [BDSP. Notice produite par INIST R0xhQV2O. Diffusion soumise à autorisation]. Background. Obesity and non-insulin-dependent diabetes mellitus (NIDDM) have increased in prevalence in Polynesian Western Samoans over the 13-year period 1978-1991, as the population undergoes an'epidemiological transition'Methods. We therefore investigated changes in the frequency of dyslipidaemia over the same period in adults aged 25-74 years, and examined factors associated with dyslipidaemia in cross-sectional and longitudinal data. Subjects were drawn from three geographically defined locations representing different degrees of modernization. Results. The age-standardized prevalence of dyslipidaemia increased in each location between 1978 (n=1197) and 1991 (n=1748), with the prevalence of hypercholesterolaemia ( 5.5 mmol/l) increasing from 18% to 36% (P<0.001), and that of hypertriglyceridaemia ( 2.0 mmol/l) increasing from 9% to 15% (P<0.001) in the capital city, Apia. In 1991 the highest serum concentrations of total, high density lipoprotein (HDL) and calculated low density lipoprotein (LDL) cholesterol were found in Poutasi (intermediate level of modernization), and the highest triglyceride levels in urbanized Apia. Higher levels of body mass index (BMI), waist-hip ratio (WHR), glucose intolerance, fasting insulin concentration, physical inactivity, educational level, and occupational status were all associated with adverse lipid levels in univariate data. (...) |
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