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Effects of smoking on the incidence of non-insulin-dependent diabetes mellitus : Replication and extension in a Japanese cohort of male employees.

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Titre :	Effects of smoking on the incidence of non-insulin-dependent diabetes mellitus : Replication and extension in a Japanese cohort of male employees. (1997)
Auteurs :	N. KAWAKAMI ; H. ISHIBASHI ; H. SHIMIZU ; N. TAKATSUKA ; Department of Public Health. Gifu University School of Medicine. Gifu. JPN
Type de document :	Article
Dans :	American journal of epidemiology (vol. 145, n° 2, 1997)
Pagination :	103-109
Langues:	Anglais
Mots-clés :	Epidémiologie ; Homme ; Tabagisme ; Japon ; Asie ; Cigarette ; Incidence ; Glande endocrine [pathologie]
Résumé :	[BDSP. Notice produite par INIST R0x48xjw. Diffusion soumise à autorisation]. The effects of smoking on the 8-year (1984-1992) incidence of non-insulin-dependent diabetes mellitus (NIDDM) were investigated in a cohort of 2,312 male employees of an electrical company in Japan. The incidence rate was 2.2/1,000 person-years. After controlling for other known risk factors for NIDDM, a proportional hazards regression analysis indicated that those who were currently smoking 16-25 cigarettes per day had a 3.27 times higher risk of developing NIDDM during the follow-up period than never smokers (p<0.05) ; the hazard ratio was similar (3.21) for those who were currently smoking 26 cigarettes per day. Among ever smokers, proportional hazards regression analysis also indicated that younger age at starting smoking was associated with an increased risk of NIDDM (p for trend=0.09). These findings suggest that number of cigarettes smoked per day is important in the relation between smoking and NIDDM incidence, although the risks did not increase above a given amount of smoking. Starting smoking at a younger age also might be independently associated with an increased risk of NIDDM.