Résumé :
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[BDSP. Notice produite par INIST-CNRS ftb38R0x. Diffusion soumise à autorisation]. Context The changing state of the health care system in the United States may be adversely affecting clinical research conducted in academic health centers (AHCs). Few formal data have been gathered about the nature and extent of the problems facing clinical research or the effects of remedies undertaken by AHCs. Objectives To assess the perceived quality and health of the clinical research enterprise and to determine challenges and adaptations to current environmental pressures. Design, Setting, and Participants Mailed survey conducted between December 1998 and March 1999 of a subsample of department chairs and senior research administrators (SRAs) in all US medical schools. Of the 712 potential respondents, 478 completed a questionnaire, yielding an overall response rate of 67.1% (64.8% for SRAs and 67.8% for department chairs). Main Outcome Measures Ratings of overall health/robustness of clinical research, quality of research in 5 domains, extent of challenges to performing research, and sense of urgency in responding to research challenges ; formal strategies for research-related tasks and their effects. Results Slightly more than half (52%) of all respondents rated the health of the clinical research enterprise as good or excellent compared with 63% for nonclinical research (P<. respondents were most likely to rate nonclinical research as high in quality compared with for phase clinical trials translational and health services all comparisons p>
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