| Titre : | Cryptosporidiosis among patients infected with human immunodeficiency virus : Factors related to symptomatic infection and survival. (1996) |
| Auteurs : | Jmjr COLFORD ; T. ARAGON ; A.M. HIROZAWA ; G.F. LEMP ; C. PETERSEN ; I.B. TAGER ; Department of Epidemiology and Biostatistics and Center for Aids Prevention Studies. University of California. San Francisco CA. USA ; Division of Public Health Biology and Epidemiology. School of Public Health. University of California. Berkeley CA. USA |
| Type de document : | Article |
| Dans : | American journal of epidemiology (vol. 144, n° 9, 1996) |
| Pagination : | 807-816 |
| Langues: | Anglais |
| Mots-clés : | Virose ; Infection ; Parasitose ; Association ; Homme ; Epidémiologie ; Survie ; Facteur risque ; Etats Unis ; Amérique ; Maladie autoimmune ; Sida |
| Résumé : | [BDSP. Notice produite par INIST x7jR0xyk. Diffusion soumise à autorisation]. The authors reviewed the medical records of 194 human immunodeficiency virus (HIV) - positive patients newly diagnosed with cryptosporidiosis and all 3,564 patients with newly diagnosed acquired immunodeficiency syndrome (AIDS) at San Francisco General Hospital for the period 1986-1992. The study was designed to address three questions : 1) How do AIDS patients who present with cryptosporidiosis differ from other patients with AIDS ? 2) What factors are associated with survival among AIDS patients with newly diagnosed cryptosporidiosis ? 3) Does a diagnosis of cryptosporidiosis impact survival after AIDS diagnosis ? A total of 194 cases of cryptosporidiosis among HIV-infected patients were identified during the study period. Of the 194 patients, 109 (56%) had no prior diagnosis of AIDS. These 109 patients represented 3.1% of the 3,564 newly diagnosed cases of AIDS in the same period. Among the 134 patients with CD4 T-lymphocyte counts performed within 3 months of Cryptosporidium diagnosis, 34 (25%) had CD4 counts greater than 209 cells/ml. In a multivariate conditional logistic regression model, the incidence of Cryptosporidium was related to ethnicity (for blacks vs. whites, matched odds ratio (OR)=0.15,95% confidence interval (CI) 0.03-0.73), CD4 count (for a CD4 count of 53 cells/ml vs.>53 cells/ml, matched OR=12.60,95% CI 4.01-39.61), and age (for a 10-year increase, matched OR=0.51,95% CI 0.27-0.98). (...) |
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