| Titre : | Association between low plasma vitamin E concentration and progression of early cortical lens opacities. (1996) |
| Auteurs : | P. ROUHIAINEN ; H. ROUHIAINEN ; J.T. SALONEN ; The Research Institute of Public Health. University of Kuopio. Kuopio. FIN |
| Type de document : | Article |
| Dans : | American journal of epidemiology (vol. 144, n° 5, 1996) |
| Pagination : | 496-500 |
| Langues: | Anglais |
| Mots-clés : | Cataracte ; Epidémiologie ; Homme ; Antioxydant ; Vitamine ; Finlande ; Europe ; Oeil [pathologie] |
| Résumé : | [BDSP. Notice produite par INIST xBR0x1Tf. Diffusion soumise à autorisation]. The authors evaluated the association between plasma vitamin E content and progression of eye lens opacities. A total of 410 hypercholesterolemic eastern Finnish men participated in the study from January 1990 to September 1993 in Kuopio, Finland. Lens opacities were classified three times at 18-month intervals using the Lens Opacities Classification System II. A low plasma vitamin E level (lowest quartile) was associated with a 3.7-fold excess risk (95% confidence interval 1.2-11.8) of the progression of early cortical lens opacities compared with the highest quartile (p=0.028). In addition, the number of cigarettes smoked daily was a significant predictor of the progression of cortical lens opacity (relative risk=1.06 per cigarette, 95% confidence interval 1.003-1.12). The progression of nuclear lens opacities was not associated with either the plasma vitamin E content or smoking. The data suggest that low plasma vitamin E content may be associated with increased risk of the progression of early cortical lens opacity. |
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