| Titre : | The relationship between plasma cholesterol concentration and minor psychiatric disturbance in the Department of the Environment Study. (1996) |
| Auteurs : | R.H. HARWOOD ; C.J. BULPITT ; A.E. FLETCHER ; H.L.J. MARKOWE ; M.G. MARMOT ; M.J. SHIPLEY ; Department of Epidemiology and Population Science. London School of Hygiene and Tropical Medicine. London. GBR |
| Type de document : | Article |
| Dans : | Journal of clinical epidemiology (vol. 49, n° 7, 1996) |
| Pagination : | 795-801 |
| Langues: | Anglais |
| Mots-clés : | Santé mentale ; Epidémiologie ; Homme ; Taux ; Cholestérol ; Lipide |
| Résumé : | [BDSP. Notice produite par INIST 70R0xYnI. Diffusion soumise à autorisation]. We examined the hypothesis that low plasma cholesterol concentration was associated with minor psychiatric disturbance in a cross-sectional study of 410 male and 138 female civil servants. Psychiatric disturbance was measured using the 30-item General Health Questionnaire (GHQ). Mean GHQ score did not vary significantly with quartile of total cholesterol concentration. After adjustment for confounding variables a significant trend of increasing mean GHQ with increasing cholesterol concentration emerged. In a logistic regression analysis subjects in the highest quartile of cholesterol concentration had an adjusted odds ratio for being a "psychiatric case" of 2.0 (95% confidence interval, 1.1-2.5) compared with those in the lowest quartile. This relationship reversed when using a higher cutoff point to define more severe cases, although the trend was not statistically significant. |
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