| Titre : | Association between use of spermicide-coated condoms and Escherichia coli urinary tract infection in young women. (1996) |
| Auteurs : | S.D. FIHN ; E.J. BOYKO ; C.L. CHEN ; J.R. GRAFTON ; M. HUNT ; E.H. NORMAND ; D. SCHOLES ; A. STERGACHIS ; P. YARBOR ; Northwest Health Services Research and Development Field Program. Veterans Affairs Medical Center. Seattle WA. USA |
| Type de document : | Article |
| Dans : | American journal of epidemiology (vol. 144, n° 5, 1996) |
| Pagination : | 512-520 |
| Langues: | Anglais |
| Mots-clés : | Contraceptif ; Contraceptif local ; Préservatif ; Complication ; Epidémiologie ; Infection ; Femme ; Homme ; Jeune adulte ; Bactérie ; Etats Unis ; Amérique |
| Résumé : | [BDSP. Notice produite par INIST BcR0xB6k. Diffusion soumise à autorisation]. Diaphragm/spermicide use increases the risk of urinary tract infection (UTI). To determine whether spermicide-coated condoms are also associated with an increased risk of UTI, the authors conducted a case-control study at a large health maintenance organization in Seattle, Washington. Cases were sexually active young women with acute UTI caused by Escherichia coli, identified from computerized laboratory files during 1990-1993. Age-matched controls were randomly selected from the enrollment files of the plan. Of 1,904 eligible women, 604 cases and 629 controls (65%) were interviewed. During the previous year, 40% of the cases and 31% of the controls had been exposed to any type of condom. The unadjusted odds ratio for UTI increased with frequency of condom exposure from 0.91 (95% confidence interval (Cl) 0.65-1.28) for weekly or less during the previous month to 2.11 (95% Cl 1.37-3.26) for more than once weekly. Exposure to spermicide-coated condoms conferred a higher risk of UTI, with odds ratios ranging from 1.09 (95% Cl 0.58-2.05) for use weekly or less to 3.05 (95% Cl 1.47-6.35) for use more than once weekly. In multivariate analyses, intercourse frequency (odds ratio (OR)=1.14 per weekly episode), history of UTI (OR=2.64), and frequency of spermicide-coated condom exposure (OR=3.34 for more than once weekly and 5.65 for use more than twice weekly) were independent predictors of UTI. (...) |
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