| Titre : | Haematopoietic cancer and medical history : a multicentre case control study. (2000) |
| Auteurs : | P. VINEIS ; A.S. COSTANTINI ; P. CROSIGNANI ; A. FONTANA ; G. MASALA ; L. MILIGI ; O. NANNI ; V. RAMAZZOTTI ; S. RODELLA ; C. SACERDOTE ; E. STAGNARO ; R. TUMINO ; C. VIGANO ; C. VINDIGNI ; Unit of Cancer Epidemiology. Ospedale S Giovanni and Cpo-Piemonte. Torino. ITA ; Unit of Epidemiology. Centre for Oncologic Prevention Cspo Firenze. ITA ; Unit of Epidemiology. National Cancer Institute. Genova. ITA ; Unit of Epidemiology. National Cancer Institute. Milano. ITA |
| Type de document : | Article |
| Dans : | Journal of epidemiology and community health (vol. 54, n° 6, 2000) |
| Pagination : | 431-436 |
| Langues: | Anglais |
| Mots-clés : | Virus ; Virose ; Infection ; Epidémiologie ; Facteur risque ; Homme |
| Résumé : | [BDSP. Notice produite par INIST 2abR0xnj. Diffusion soumise à autorisation]. Background-Viruses (such as Epstein-Barr virus) and pathological conditions (mainly involving immunosuppression) have been shown to increase the risk of haematolymphopoietic malignancies. Other associations (diabetes, tonsillectomy, autoimmune diseases) have been inconsistently reported. Methods-The association between different haematolymphopoietic malignancies (lymphomas, myelomas and leukaemias) and the previous medical history has been studied in a population-based case-control investigation conducted in Italy, based on face to face interviews to 2669 cases and 1718 population controls (refusal rates 10% and 19%, respectively). Controls were a random sample of the general population. Results-Previous findings were confirmed concerning the association between non-Hodgkin's lymphoma (NHL) and lupus erythematosus (odds ratio, OR=8.4 ; 95% CI 1.6,45), tuberculosis (OR=1.6 ; 1.05,2.5) and hepatitis (1.8 ; 1.4,2.3). An association was found also between NHL and maternal (OR=2.8 ; 1.1,6.9) or paternal tuberculosis (OR=1.7 ; 0.7,3.9). Odds ratios of 4.0 (1.4,11.8) and 4.4 (1.1,6.6) were detected for the association between NHL and Hodgkin's disease, respectively, and previous infectious mononucleosis, but recall bias cannot be ruled out. No association was found with diabetes, tonsillectomy and adenoidectomy. An association with malaria at young age and "low grade" lymphatic malignancies is suggested. (...) |
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