| Titre : | Information presentation and decisions to enter clinical trials : a hypothetical trial of hormone replacement therapy. (2000) |
| Auteurs : | J.A. WRAGG ; R.J. LILFORD ; E.J. ROBINSON ; School of Psychology. University of Birmingham. Edgbaston Birmingham. GBR |
| Type de document : | Article |
| Dans : | Social science and medicine (vol. 51, n° 3, 2000) |
| Pagination : | 453-462 |
| Langues: | Anglais |
| Mots-clés : | Essai thérapeutique ; Hormone ; Participation ; Malade ; Evaluation ; Homme |
| Résumé : | [BDSP. Notice produite par INIST R0xlv9ns. Diffusion soumise à autorisation]. We examined recruitment to an imaginary trial of hormone replacement therapy (HRT) following two different styles of information about HRT. We predicted that for treatments which, like HRT, are available outside a trial, people offered the facts as currently known would be less likely to remain unsure about the relative costs and benefits, and so less likely to agree to enter a randomised trial. In contrast, when the information provided reflected the current state of uncertainty which justified the trial, we predicted that people would be less likely to form a preference for one treatment arm over the other, and so more likely to agree to enter a trial. One hundred women aged 25-40 years were informed about HRT via a video and an information leaflet. For half the participants the information was framed in a way which emphasised the current state of uncertainty about the relative costs and benefits of HRT, and in that respect it reflected the justification for a trial. This version was considered to be similar in style to information commonly provided to potential trial participants. For half the participants the same information was framed in a way which offered explicit numerical detail about currently known facts, and in that respect it was considered to be similar in style to information commonly available to doctors prior to a trial. (...) |
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