| Titre : | Comparison of weight in middle age, weight at 18 years, and weight change between, in predicting subsequent 14 year mortality and coronary events : Caerphilly Prospective study. (2000) |
| Auteurs : | J.W.G. YARNELL ; C.C. PATTERSON ; P.M. SWEETNAM ; H.F. Thomas ; Department of Epidemiology and Public Health. Queen's University of Belfast. Mulhouse Building. Ics. Belfast. GBR ; Mrc Epidemiology Unit South Wales Llandough Hospital. Cardiff. GBR |
| Type de document : | Article |
| Dans : | Journal of epidemiology and community health (vol. 54, n° 5, 2000) |
| Pagination : | 344-348 |
| Langues: | Anglais |
| Mots-clés : | Obésité ; Homme ; Epidémiologie ; Cardiopathie coronaire ; Facteur risque ; Mortalité ; Prise poids ; Maladie nutrition ; Appareil circulatoire [pathologie] |
| Résumé : | [BDSP. Notice produite par INIST qR0x1hi1. Diffusion soumise à autorisation]. Objective-The prevalence of obesity is increasing in many European countries and in the United States. This report examines the mortality and morbidity associated with being overweight and obese in the Caerphilly Prospective Study and the relative effects of weight in middle age and self reported weight at 18 years. Design-All men aged 45 to 59 years from the town of Caerphilly, South Wales and outlying villages were identified and 2512 men were examined for the first time between 1979 and 1983. Men were asked to recall their weight at 18 years of age (when the majority had been examined for National Service) so that weight then, weight at screening, and the difference could be related to their 14 year follow up from screening. A total of 2335 men could recall their weight at 18 years. By 14 years of follow up from screening 465 men had died and 382 had had coronary events. Results-Mean body mass index in men who reported their weight at 18 years was 22.3 (SD 2.8) kg/m2 and only 41 of these men (1.8%) were classified as obese (index >= 30 kg/m2). The index did not predict all cause mortality when examined by quintile. For major ischaemic heart disease (non-fatal or fatal ischaemic heart disease) the relative odds was 1.73 (95% CI 1.21,2.48) in the top fifth of the distribution (body mass index >= 24.2 kg/m2) compared with the bottom fifth (body mass index<20.1 kg/m2). In men with an index >= 30 kg/m2 however, the relative odds were 2.03 (95% CI, 1.03,4. (...) |
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