| Titre : | Patterns of alcohol drinking and all-cause mortality : Results from a large-scale population-based cohort study in Japan. (2007) |
| Auteurs : | Tomomi MARUGAME ; Manami INOUE ; Tomotaka SOBUE ; Shoichiro TSUGANE ; Seiichiro YAMAMOTO ; YOSHIMI (Itsuro) : JPN. Tobacco Control Information Section. Center for Information Research & Library. National Institute of Public Health. Saitama. ; National Cancer Center. Center for Cancer Control and Information Services. Cancer Information Services and Surveillance Division. Tokyo. JPN ; National Cancer Center. Research Center for Cancer Prevention and Screening. Epidemiology and Prevention Division. Tokyo. JPN |
| Type de document : | Article |
| Dans : | American journal of epidemiology (vol. 165, n° 9, 2007) |
| Pagination : | 1039-1046 |
| Langues: | Anglais |
| Mots-clés : | Alcool ; Facteur ; Mortalité ; Epidémiologie ; Population ; Japon ; Asie ; Comportement ; Homme |
| Résumé : | [BDSP. Notice produite par INIST-CNRS 6g5R0xRB. Diffusion soumise à autorisation]. To evaluate the hypothesis that, in terms of all-cause death, drinking alcohol 1-4 days per week is less harmful than daily (5-7 days/week) drinking of the same quantity of alcohol, a prospective cohort study using a self-administered questionnaire was conducted in Japan between 1990 and 2003 of 88,746 subjects (41,702 men and 47,044 women) aged 40-69 years at baseline. Among male regular drinkers consuming alcohol more than 1 day per week, light drinkers (<300 g/week) showed no increase in all-cause mortality irrespective of frequency of alcohol intake. Heavy drinkers (>=300 g/week), however, showed an increased risk of all-cause mortality among those who consumed alcohol 5-7 days per week, while no obvious increase was observed among those who consumed alcohol less than 4 days per week. Hazard ratios for drinkers who consumed alcohol 5-7 days per week were 1.29 (95% confidence interval : 1.12,1.50) for 300-449 g per week and 1.55 (95% confidence interval : 1.32,1.81) for>450 g per week when compared with those for occasional drinkers who consumed alcohol 1-3 days per month. These findings support the Japanese social belief that "liver holidays," abstaining from alcohol for more than 2 days per week, are important for heavy drinkers. |
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