Résumé :
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[BDSP. Notice produite par INIST-CNRS 9lEmR0xO. Diffusion soumise à autorisation]. Despite high single-dose measles immunization coverage since the 1980s and high 2-dose coverage since 1995, Romania experienced a measles epidemic between November 1996 and June 1998. Apart from unvaccinated children younger than 2 years, the largest numbers of cases accured among persons aged 8 through 1-years, 73% of whom had previously been vaccinated. Vaccine effectiveness stidies conducted during the epidemic found the measles vaccine to be highly effective, indicating that measles among vaccinated school aged children was primarly due to failure to respond to a single dose of measles vaccine. A nationwide campaign was conducted to immunize school-aged children was primarily due to failure to respond to a single dose of measles vaccine. A nationwide campaign was conducted to immunize school-aged children, most of whom were not immunized under the second-dose policy established in 1994 (persons aged 10-18 years). This campaignn apperars to have reduced susceptibility to levels required to prevent further measles outbreaks and interrupt the transmission of indigenous measles. Preschool-aged children were not included, because the campaign should decrease measles transmission and reduce the risk of exposure among preschool-aged children, who are now covered by the routine 2-dose schedule. Because of the size of the campagn and the goal of the World Health Oragnization's (WHO's) European region to eliminate measles by 2007, special efforts were made to monitor Romania's experience.
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