| Titre : | Is open-angle glaucoma associated with early menopause ? The Rotterdam Study. (2001) |
| Auteurs : | Caroline-Aa HULSMAN ; Paulus-Tvm DE JONG ; Albert HOFMAN ; Raan-S RAMRATTAN ; Johannes-R VINGERLING ; Iris-Cd WESTENDORP ; Jacqueline-Cm WITTEMAN ; Roger-Cw WOLFS ; Department of Epidemiology and Biostatistics. Erasmus University Medical School. Rotterdam. NLD ; Department of Ophthalmology. Erasmus University Medical School. Rotterdam. NLD ; The Netherlands Ophthalmic Research Institute. Amsterdam. NLD |
| Type de document : | Article |
| Dans : | American journal of epidemiology (vol. 154, n° 2, 2001) |
| Pagination : | 138-144 |
| Langues: | Anglais |
| Mots-clés : | Homme ; Femme ; Epidémiologie ; Europe ; Facteur risque ; Oeil [pathologie] ; Pays Bas |
| Résumé : | [BDSP. Notice produite par INIST-CNRS MGzOR0xj. Diffusion soumise à autorisation]. The authors examined the association between age at menopause and open-angle glaucoma among women aged>=55 years in the population-based Rotterdam Study (1990-1993). Information on age and type of menopause was obtained by interview. Subjects (n=3,078) were stratified into three categories according to age at menopause :<45 years, 45-49 years, and>=50 years, with the last group serving as the reference group. Diagnosis of open-angle glaucoma was based on the presence of a glaucomatous visual field defect and glaucomatous optic neuropathy. Open-angle glaucoma was diagnosed in 78 women with a natural menopause and 15 women with an artificial menopause. In the category of natural menopause, women who went through menopause before reaching the age of 45 years had a higher risk of open-angle glaucoma than the reference group (odds ratio=2.6 ; 95% confidence interval : 1.5,4.8), after adjustment for age and use of hormone replacement therapy. Among women who went through menopause between the ages of 45 and 49 years, the odds ratio was 1.1 (95% confidence interval : 0.7,2.0). These findings suggest that early menopause is associated with a higher risk of open-angle glaucoma. |
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