| Titre : | Long-term outcome of myocardial infarction in women and men : A population perspective. (2000) |
| Auteurs : | Viola VACCARINO ; Lisa F. Berkman ; Harlan-M KRUMHOLZ ; Department of Health and Social Behavior. Harvard School of Public Health. Boston. MA. USA |
| Type de document : | Article |
| Dans : | American journal of epidemiology (vol. 152, n° 10, 2000) |
| Pagination : | 965-973 |
| Langues: | Anglais |
| Mots-clés : | Infarctus ; Myocarde ; Pronostic ; Long terme ; Mortalité ; Homme ; Sexe ; Appareil circulatoire [pathologie] ; Cardiopathie coronaire ; Myocarde [pathologie] |
| Résumé : | [BDSP. Notice produite par INIST TBR0x50D. Diffusion soumise à autorisation]. Because of women's survival advantage, the impact of myocardial infarction (MI) on long-term mortality in women compared with men may be underestimated. The authors examined this issue in a community sample of 2,462 persons aged >=65 years living in New Haven, Connecticut, who were free of MI at baseline and were followed for 10 years (1982-1992). By using proportional hazards models with MI hospitalizations and the sex-MI interaction as time-dependent covariables, survival for the MI cases from the date of Ml was compared with survival of persons who, at the same follow-up time, were still alive and free of Ml. Women survived longer than men mainly in the absence of Ml. The multivariable-adjusted hazard ratios of death were 0.53 in the absence and 0.87 in the presence of Ml, and MI was associated with a greater risk of death in women (adjusted hazard ratio=5.9) than in men (adjusted hazard ratio=3.6) (p=0.01 for the sex-MI interaction). When out-of-hospital fatal infarctions were considered, the impact of MI on survival in women compared with men increased. In conclusion, in this elderly cohort, when viewed from a population perspective, Ml had a greater impact on mortality in women and significantly narrowed women's typical survival advantage over men. |
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