Résumé :
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[BDSP. Notice produite par INIST-CNRS MwecR0x0. Diffusion soumise à autorisation]. Context Influenza and respiratory syncytial virus (RSV) cause substantial morbidity and mortality. Statistical methods used to estimate deaths in the United States attributable to influenza have not accounted for RSV circulation. Objective To develop a statistical model using national mortality and viral surveillance data to estimate annual influenza-and RSV-associated deaths in the United States, by age group, virus, and influenza type and subtype. Design, Setting, and Population Age-specific Poisson regression models using national viral surveillance data for the 1976-1977 through 1998-1999 seasons were used to estimate influenza-associated deaths. Influenza-and RSV-associated deaths were simultaneously estimated for the 1990-1991 through 1998-1999 seasons. Main Outcome Measures Attributable deaths for 3 categories : underlying pneumonia and influenza, underlying respiratory and circulatory, and all causes. Results Annual estimates of influenza-associated deaths increased significantly between the 1976-1977 and 1998-1999 seasons for all 3 death categories (P<. for each category the through seasons greatest mean numbers of deaths were associated with influenza a viruses followed by rsv b and respectively annual means underlying pneumonia respiratory circulatory all-cause deaths. influenza-and rsv-associated occurred among persons aged years or older. was more than in all age groups except children younger year. on average times as many rsv. conclusions mortality both circulation disproportionately affects elderly persons. have increased substantially last decades part because aging population underscoring need better prevention measures including effective vaccines vaccination programs>
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