| Titre : | Alcohol, smoking, coffee and risk of non-fatal acute myocardial infarction in Italy. (2001) |
| Auteurs : | Alessandra TAVANI ; Michaela BERTUZZI ; Carlo LA VECCHIA ; Eva NEGRI ; Loredana SORBARA ; Istituto di Ricerche. Farmacologiche'Mario Negri'Milan. ITA |
| Type de document : | Article |
| Dans : | European journal of epidemiology (vol. 17, n° 12, 2001) |
| Pagination : | 1131-1137 |
| Langues: | Anglais |
| Mots-clés : | Infarctus ; Myocarde ; Tabagisme ; Consommation alimentaire ; Café ; Alcool ; Epidémiologie ; Facteur risque ; Homme ; Italie ; Europe ; Thé ; Appareil circulatoire [pathologie] ; Cardiopathie coronaire ; Myocarde [pathologie] |
| Résumé : | [BDSP. Notice produite par INIST-CNRS AuDR0xPX. Diffusion soumise à autorisation]. Objectives : To assess the relation between cigarette smoking, alcohol, coffee, decaffeinated coffee and tea consumption, and the risk of non-fatal acute myocardial infarction (AMI). Design and setting : Hospital-based case-control study conducted in 1995-1999 in Milan, Italy. Patients : 507 cases with a first episode of non-fatal AMI, and 478 controls admitted to hospital for acute diseases. Methods : Information was collected by interviewer-administered questionnaires. Odds ratios (OR) and 95% confidence intervals (CI) were calculated by multiple logistic regression. Results : Compared to alcohol non-drinkers the OR was 0.6 (95% CI : 0.4-0.9) in drinkers, and 0.5 in drinkers of>3 drinks/day. The OR for>1 drink/day of wine was 0.5, and those for beer, amari, grappa and spirits ranged between 0.4 and 0.6. Compared to never smokers, the OR was 2.2 (95% CI : 1.5-3.1) among current smokers, and 4.6 among current smokers of>=25 cigarettes/day. The risk was similar to that of never smokers>=5 years after cessation (OR : 1.1 after 5-9 years, 0.7 after>=10 years). The OR was 2.3 for low tar cigarettes and 2.0 for high tar ones. The OR for coffee intake (expresso and mocha) was around unity up to 3 cups/day, but rose to 1.9 (95% CI : 1.1-3.3) for>=6 cups/day. Moderate decaffeinated coffee and tea intake was not associated with AMI risk. Compared to non-smokers drinking<=3 cups of coffee/day, the OR was 1.6 among non-smokers drinking>3 cups of coffee/day and 3.3 (95% CI : 2.1-5.0) among current smokers drinking>3 cups of coffee/day. Compared to alcohol drinkers with a coffee intake of<=3 cups/day, alcohol non-drinkers with higher coffee intake had an OR of 2.2, and compared to non-smokers alcohol drinkers, the OR was 3.3 in current smokers alcohol non-drinkers. Conclusions : In this Italian population alcohol intake was inversely associated to AMI risk, while smoking and heavy (but not moderate) coffee drinking increased the risk. |
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