| Titre : | Relation between heavy and binge drinking and all-cause and cardiovascular mortality in Novosibirsk, Russia : a prospective cohort study. (2002) |
| Auteurs : | Sofia MALYUTINA ; Martin BOBAK ; Valery GAFAROV ; Svetlana KURILOVITCH ; Michael Marmot ; Yuri NIKITIN ; Galina SIMONOVA ; Institute of Internal Medicine. Siberian Branch of the Russian Academy of Medical Sciences. Novosibirsk. RUS |
| Type de document : | Article |
| Dans : | Lancet (The) (vol. 360, n° 9344, 2002) |
| Pagination : | 1448-1454 |
| Langues: | Anglais |
| Mots-clés : | Alcoolisme ; Complication ; Mortalité ; Appareil circulatoire [pathologie] ; Epidémiologie ; Russie ; Homme |
| Résumé : | [BDSP. Notice produite par INIST-CNRS wAukR0xL. Diffusion soumise à autorisation]. Background Moderate alcohol consumption is associated with reduced cardiovascular mortality, but binge drinking is thought to be detrimental. We examined effects of heavy and binge drinking in a population with high rates of binge drinking. Methods We did a prospective cohort study in Novosibirsk, Russia, in 6502 men aged 25-64 years at baseline who were examined in WHO MONICA (monitoring trends and determinants in cardiovascular disease surveys) in 1985/86,1988/89, and 1994/95, and in a pilot study in 1984. We assessed alcohol intake and drinking pattern by questionnaire ; binge drinking was defined as consumption of 160 g or greater of pure alcohol on a typical occasion. Participants were followed-up for a median of 9.5 years (range 3.1-15.2). Findings There were 836 deaths in the cohort, 395 of which resulted from cardiovascular diseases. Prevalence of binge drinking at baseline was 16% (n=1005). Adjusted relative risks for binge drinking at least once a month (compared with consumption of<80 g pure alcohol) were 1.05 (95% Cl 0.80-1.36) for deaths from all causes, 0.99 (0.66-1.50) for deaths from cardiovascular disease, 1.27 (0.81-1.99) for deaths from coronary heart disease, and 2.08 (1.08-3.99) for death from external causes. Risk of total and cardiovascular mortality was raised in a small group of frequent heavy drinkers (5% [264] of all drinkers) ; for this group, adjusted relative risks were 1.61 (1.04-2.50) for total mortality and 2.05 (1.09-3.86) for deaths from cardiovascular disease. Interpretation The risk of death from cardiovascular disease seems to be increased in frequent heavy drinkers, but is not necessarily associated with episodic binge drinking. |
Service Documentation EHESP
Me connecter
PORTAIL DOCUMENTAIRE
École des hautes études en santé publique
Catalogue
Multi-bases
Accueil
Sélection de la langue
Adresse
Service Documentation EHESPBibliothèque Rennes Avenue du Professeur Léon Bernard – CS 74312 – 35043 Rennes Cedex Bibliothèque MSSH Paris 20 avenue George Sand - 93210 La Plaine Saint-Denis
France
Bibliothèque Rennes : 02 99 02 29 50 Bibliothèque MSSH Paris : 02 99 02 24 50
contact