| Titre : | Chinese Herbal Medicine and interferon in the treatment of chronic hepatitis B : A meta-analysis of randomized, controlled trials. (2002) |
| Auteurs : | Michael MCCULLOCH ; Michael BROFFMAN ; John-Mjr COLFORD ; . JIN GAO ; Institute of Biophysics. China Academy of Sciences. Beijing. CHN ; Pine Street Clinic. San Anselmo. CA. USA |
| Type de document : | Article |
| Dans : | American journal of public health (vol. 92, n° 10, 2002) |
| Pagination : | 1619-1627 |
| Langues: | Anglais |
| Mots-clés : | Hépatite virale B ; Virose ; Infection ; Virus ; Interféron ; Chimiothérapie ; Plante médicinale ; Homme ; Appareil digestif [pathologie] ; Foie [pathologie] |
| Résumé : | [BDSP. Notice produite par INIST-CNRS 0pm1cR0x. Diffusion soumise ... autorisation]. Objectives. This meta-analysis was conducted to examine the effectiveness of Chinese herbal medicine (either alone or with interferon alfa) in treating chronic hepatitis B. Methods. We searched the TCMLARS, AMED, CISCOM, EMBASE, MEDLINE, and Cochrane Collaboration databases and then hand-searched the articles'bibliographies. Results. Chinese herbal medicine significantly increased seroreversion of HBsAg and was equivalent to interferon alfa in seroreversion of HBeAg and hepatitis B virus (HBV) DNA ; Chinese herbal medicine combined with interferon alfa significantly increased seroreversion of HBsAg, HBeAg, and HBV DNA. The Chinese herbal medicine active component bufotoxin combined with interferon alfa significantly increased HBeAg and HBV DNA seroreversion. The Chinese herbal medicine active component kurorinone was equivalent to interferon alfa in seroreversion of HBeAg and HBV DNA. Conclusions. Although the quality of existing studies was poor, these data suggest that further trials of Chinese Herbal Medicine and interferon in chronic hepatitis B infection are justified. |
Service Documentation EHESP
Me connecter
PORTAIL DOCUMENTAIRE
École des hautes études en santé publique
Catalogue
Multi-bases
Accueil
Sélection de la langue
Adresse
Service Documentation EHESPBibliothèque Rennes Avenue du Professeur Léon Bernard – CS 74312 – 35043 Rennes Cedex Bibliothèque MSSH Paris 20 avenue George Sand - 93210 La Plaine Saint-Denis
France
Bibliothèque Rennes : 02 99 02 29 50 Bibliothèque MSSH Paris : 02 99 02 24 50
contact