| Titre : | The Perinatal Guidelines evaluation project HIV and Pregnancy study : Overview and cohort description. (2002) |
| Auteurs : | Kathleen-A ETHIER ; Misabel Fernandez ; Jeannette-R ICKOVICS ; Linda-J KOENIG ; Rachel-A ROYCE ; Tracey-E WILSON ; Department of Epidemiology and Public Health. Yale School of Medicine. And Center for Interdisciplinary Research on Aids. New Haven. CT. USA |
| Type de document : | Article |
| Dans : | Public health reports (vol. 117, n° 2, 2002) |
| Pagination : | 137-147 |
| Langues: | Anglais |
| Mots-clés : | Sida ; Virose ; Infection ; VIH ; Rétrovirus ; Virus ; Homme ; Femme ; Grossesse ; Evaluation ; Prévention santé ; Stress ; Enfant ; Etat dépressif ; Immunopathologie ; Trouble humeur ; Facteur psychosocial |
| Résumé : | [BDSP. Notice produite par INIST-CNRS 6VR0x554. Diffusion soumise ... autorisation]. Objective. The HIV and Pregnancy Study of the Perinatal Guidelines Evaluation Project is a prospective, longitudinal, multisite study established to : (a) assess the implementation of Public Health Service guidelines regarding the prevention of perinatal HIV transmission and (b) evaluate the psychosocial consequences of HIV infection among pregnant women. A distinctive aspect of the study is the use of an HIV-negative comparison group. This article describes the methodology of the study and baseline characteristics of the study sample. Methods and Results. HIV-infected (n=336) and uninfected (n=298) pregnant women were enrolled from four geographic areas : Connecticut, North Carolina, Brooklyn, NY, and Miami, FL. The study included three structured face-to-face interviews from late pregnancy to six months postpartum for HIV-infected and uninfected women. Additional self-reports of medication adherence were collected for the HIV-infected participants, and the medical records of infected mothers and their infants were reviewed. Electronic monitoring of medication adherence was conducted for a subset of the infected women. The groups were successfully matched on self-reported characteristics, including HIV-risk behaviors. More than half of the uninfected women reported a high-risk sexual partner. Baseline comparisons indicated that both the HIV-infected and uninfected women had high levels of depressive symptoms, stress, and recent negative life events. Conclusions. This study provides a unique description of the psychosocial and behavioral characteristics of a population of low-income women. The results of this study suggest that HIV infection is one of many stressors faced by the women in this study. |
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