| Titre : | Women's exposure to early and later life socioeconomic disadvantage and coronary heart disease risk : the Stockholm Female Coronary Risk Study : Socioeconomic differentials in health. (2001) |
| Auteurs : | Sarah-P WAMALA ; George-A KAPLAN ; John LYNCH ; Department of Epidemiology. School of Public Health. University of Michigan. Ann Arbor. USA |
| Type de document : | Article |
| Dans : | International journal of epidemiology (vol. 30, n° 2, 2001) |
| Pagination : | 275-284 |
| Langues: | Anglais |
| Mots-clés : | Cardiopathie coronaire ; Facteur socioéconomique ; Exposition ; Epidémiologie ; Facteur risque ; Homme ; Femme ; Suède ; Europe ; Appareil circulatoire [pathologie] |
| Résumé : | [BDSP. Notice produite par INIST KFkQuR0x. Diffusion soumise à autorisation]. Background Measures of low socioeconomic position have been associated with increased risk for coronary heart disease (CHD) among women. A more complete understanding of this association is gained when socioeconomic position is conceptualized from a life course perspective where socioeconomic position is measured both in early and later life. We examined various life course socioeconomic indicators in relation to CHD risk among women. Methods The Stockholm Female Coronary Risk Study is a population-based case-control study, in which 292 women with CHD aged <=65 years and 292 age-matched controls were investigated using a wide range of socioeconomic, behavioural, psychosocial and physiological risk factors. Socioeconomic disadvantage in early life (large family size in childhood, being born last, low education), and in later life (housewife or blue-collar occupation at labour force entry, blue-collar occupation at examination, economic hardships prior to examination) was assessed. Results Exposure to early (OR=2.65,95% CI : 1.12-6.54) or later (OR=5.38,95% CI : 2.01-11.43) life socioeconomic disadvantage was associated with increased CHD risk as compared to not being exposed. After simultaneous adjustment for marital status and traditional CHD risk factors, early and later socioeconomic disadvantage, exposure to three instances of socioeconomic disadvantage in early life was associated with an increased CHD risk of 2.48 (95% CI : 0.90-6.83) as compared to not being exposed to any disadvantage. The corresponding adjusted risk associated with exposure to later life disadvantage was 3.22 (95% CI : 1.02-10.53). Further analyses did not show statistical evidence of interaction effects between early and later life exposures (P=0.12), although being exposed to both resulted in a 4.2-fold (95% CI : 1.4-12.1) increased CHD risk. (...) |
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