| Titre : | Lifelong teetotallers, ex-drinkers and drinkers : Mortality and the incidence of major coronary heart disease events in middle-aged British men. (1997) |
| Auteurs : | S.G. WANNAMETHEE ; A.G. SHAPER ; Division of Research. Kaiser Permanente Medical Care Program. Northern California Region. Oakland. CA. USA |
| Type de document : | Article |
| Dans : | International journal of epidemiology (vol. 26, n° 3, 1997) |
| Pagination : | 523-531 |
| Langues: | Anglais |
| Mots-clés : | Consommation ; Boisson alcoolisée ; Abstinence ; Cardiopathie coronaire ; Mortalité ; Epidémiologie ; Incidence ; Facteur risque ; Homme ; Royaume Uni ; Europe ; Etude comparée ; Appareil circulatoire [pathologie] |
| Résumé : | [BDSP. Notice produite par INIST ByR0xnJg. Diffusion soumise à autorisation]. Background. To determine the risk of all cause mortality and the incidence of major coronary heart disease (CHD) events in lifelong teetotallers and in ex-drinkers compared with occasional and regular drinkers. Methods. A prospective study of middle-aged men drawn at random from one general practice in each of 24 British towns. Five years after the screening of 7735 men aged 40-59 years, 7167 provided further information on postal questionnaire enabling separation of non-drinkers into lifelong teetotallers and ex-drinkers. Results. During the follow-up period of 9.8 years after the postal questionnaire there were 929 deaths from all causes and 490 major CHD events. Ex-drinkers exhibited increased cardiovascular and non-cardiovascular mortality ; lifelong teetotallers showed the lowest cardiovascular mortality but a significantly increased non-cardiovascular mortality. After adjustment for confounding factors and pre-existing disease, the two non-drinking groups did not differ significantly in all cause mortality from occasional and regular drinkers (light, moderate or heavy) but lifelong teetotallers still showed a significant increase in non-cardiovascular mortality. Adjustment considerably attenuated the risk of both cardiovascular and non-cardiovascular mortality in the ex-drinkers. (...) |
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