| Titre : | Ethnic distribution of Chlamydophila pneumoniae antibodies in a Malaysian population and possible correlation with coronary heart disease. (2003) |
| Auteurs : | Brindha-R NAIDU ; Y.F. NGEOW ; T. PANG |
| Type de document : | Article |
| Dans : | European journal of epidemiology (vol. 18, n° 2, 2003) |
| Pagination : | 135-137 |
| Langues: | Anglais |
| Mots-clés : | Cardiopathie coronaire ; Malaisie ; Asie ; Homme ; Bactérie ; Ethnie ; Séropositivité ; Epidémiologie ; Etiologie ; Appareil circulatoire [pathologie] |
| Résumé : | [BDSP. Notice produite par INIST-CNRS qr4AR0xq. Diffusion soumise à autorisation]. Chlamydophila pneumoniae, an important respiratory pathogen causing lower respiratory tract infections, has also been implicated in coronary heart disease (CHD). This study reports a cross-sectional, demographic, serological analysis of the prevalence of Chlamydophila pneumoniae antibodies in a multiracial Malaysian population. Generally, Malaysian Indians had the highest degree of seropositivity (58%) followed by the Chinese (54%) and the Malays (32%), results which were statistically significant (CI : 95% ; p<0.01). Interestingly, this trend was also reflected in the study group consisting of patients with acute myocardial infarctions (AMI) and chronic CHD. Again, the Indians were more frequently sero-positive (65%), with more than 50% having IgG titres>128. Comparatively, the Chinese and Malays showed 51 and 17% seropositivity respectively. These results were also statistically significant (CI : 95% ; p<0.01). Malaysian Indians are more commonly afflicted with CHD. A variety of factors have been suggested to explain this prevalence including diet, social habits, genetics and the possible role of infectious agents. This study notes an interesting association between this pattern of racial prevalence and the possible role of C. pneumoniae infections as a contributory/predisposing factor in the development of cardiovascular disease. |
Service Documentation EHESP
Me connecter
PORTAIL DOCUMENTAIRE
École des hautes études en santé publique
Catalogue
Multi-bases
Accueil
Sélection de la langue
Adresse
Service Documentation EHESPBibliothèque Rennes Avenue du Professeur Léon Bernard – CS 74312 – 35043 Rennes Cedex Bibliothèque MSSH Paris 20 avenue George Sand - 93210 La Plaine Saint-Denis
France
Bibliothèque Rennes : 02 99 02 29 50 Bibliothèque MSSH Paris : 02 99 02 24 50
contact