Titre :
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A one-generation cluster of malignant mesothelioma within a family reveals exposure to asbestos-contaminated jute bags in Naples, Italy. (2003)
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Auteurs :
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V. ASCOLI ;
C. CAMOVALE-SCALZO ;
EFRATI (C.) : ITA. Dipartimento di Medicina Clinica. Univerità La Sapienza. Roma. ;
MENEGOZZO (M.) : ITA. Sezione di Medicina del Lavoro. Dipartimento di Medicina Sperimentale. Ii Università di Napoli. Napoli. ;
F. NARDI ;
Anatomia Patologica. Dipartimento di Medicina Sperimentale e Patologia. Roma. ITA
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Type de document :
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Article
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Dans :
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European journal of epidemiology (vol. 18, n° 2, 2003)
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Pagination :
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171-174
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Langues:
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Anglais
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Mots-clés :
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Asbestose
;
Italie
;
Europe
;
Homme
;
Epidémiologie
;
Cancer
;
Appareil respiratoire [pathologie]
;
Pneumoconiose
;
Maladie professionnelle
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Résumé :
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[BDSP. Notice produite par INIST-CNRS IER0xOx4. Diffusion soumise à autorisation]. Substantial evidence supports the role of asbestos in malignant mesothelioma. Clustering for this malignancy among relatives not only suggests genetic susceptibility as a relevant component but also provides a clue to investigate non-occupational sources of exposure. We identified five cases of malignant mesothelioma within one family with exposure to asbestos experienced during childhood, as'next door'residents of a workshop recycling asbestos-contaminated jute sacks in Naples, Italy. This cluster discloses the health risk in the reuse of bags that previously had contained asbestos. Furthermore, it emphasizes the role of asbestos in the genetic-environmental interaction issue of malignant mesothelioma.
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