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Article
Lindsay FERNANDEZ-RHODES ; Ellen-W DEMERATH ; Diana-L COUSMINER ; . RAN TAO ; Jill-G DREYFUS ; Tonu ESKO ; Albert-V Smith ; Vilmundur GUDNASON ; Tamara-B HARRIS ; Lenore LAUNER ; Patrick-F MCARDLE ; Laura-M YERGES-ARMSTRONG ; Cathy-E ELKS ; David-P STRACHAN ; Zoltán KUTALIK ; Peter VOLLENWEIDER ; Bjarke FEENSTRA ; Heather-A BOYD ; Andres METSPALU ; Evelin MIHAILOV ; Linda BROER ; Mcarola ZILLIKENS ; Ben OOSTRA ; Cornelia-M VAN DUIJN ; Kathryn-L LUNETTA ; John-Rb PERRY ; Anna MURRAY ; Daniel-L KOLLER ; . DONGBING LAI ; Tanguy CORRE ; Daniela TONIOLO ; Eva Albrecht ; Doris STOCKL ; Harald GRALLERT ; Christian GIEGER ; Caroline HAYWARD ; Ozren POLASEK ; Igor RUDAN ; James-F WILSON ; . CHUNYAN HE ; Peter KRAFT ; Frank-B HU ; David J. Hunter ; Jouke-Jan HOTTENGA ; Gonneke WILLEMSEN ; Dorret-I BOOMSMA ; Enda-M BYRNE ; Nicholas-G Martin ; Grant-W MONTGOMERY ; Nicole-M WARRINGTON ; Craig-E PENNELL ; Lisette STOLK ; Jenny-A VISSER ; Albert HOFMAN ; André-G UITTERLINDEN ; Fernando RIVADENEIRA ; . PENG LIN ; Sherri-L FISHER ; Laura-J BIERUT ; Laura CRISPONI |[BDSP. Notice produite par INIST-CNRS kCR0xFCE. Diffusion soumise à autorisation]. Obesity is of global health concern. There are well-described inverse relationships between female pubertal timing and obesity. Recent genome-wide association stu[...]
Article
Linda BROER ; Najaf AMIN ; M. ARFAN IKRAM ; Monique-Mb BRETELER ; Albert HOFMAN ; KOUDSTAAL (Peter-J) : NLD. Deparment of Neurology. Erasmus Medical Center. Rotterdam. ; Ben-A OOSTRA ; Fernando RIVADENEIRA ; André-G UITTERLINDEN ; Cornelia-M VAN DUIJN |[BDSP. Notice produite par INIST-CNRS roDIR0xr. Diffusion soumise à autorisation].
Article
Suman KUNDU ; Yurii-S AULCHENKO ; Acecile-Jw JANSSENS ; Cornelia-M VAN DUIJN ; Department of Epidemiology. Rotterdam. NLD |[BDSP. Notice produite par INIST-CNRS R0xmnGmJ. Diffusion soumise à autorisation]. The rapid identification of genetic markers for multifactorial diseases from genome-wide association studies is fuelling interest in investigating the predictive [...]
Article
Acecile-Jw JANSSENS ; Sara BEDROSIAN ; Paolo BOFFETTA ; Siobhan-M DOLAN ; Nicole DOWLING ; Isabel Fortier ; Andrew-N FREEDMAN ; Jeremy-M GRIMSHAW ; Jeffrey GULCHER ; Marta GWINN ; Mark-A HLATKY ; John-Pa IOANNIDIS ; Holly JANES ; Muin-J KHOURY ; Peter KRAFT ; Julian LITTLE ; Stephanie MELILLO ; Christopher-J O'DONNELL ; Michael-J PENCINA ; David RANSOHOFF ; Sheri-D SCHULLY ; Daniela SEMINARA ; Cornelia-M VAN DUIJN ; Deborah-M WINN ; Caroline-F WRIGHT ; Department of Epidemiology. Erasmus University Medical Center. CA Rotterdam. NLD ; Office of Public Health Genomics. Centers for Disease Control and Prevention. Atlanta GA. USA |[BDSP. Notice produite par INIST-CNRS R0xIJk8j. Diffusion soumise à autorisation]. The rapid and continuing progress in gene discovery for complex diseases is fuelling interest in the potential application of genetic risk models for clinical and[...]
Article
Acecile-Jw JANSSENS ; IOANNIDIS (John-Pa) : GRC. Department of Hygiene and Epidemiology. University of Ioannina School of Medicine. Ioannina. ; KHOURY (Muin-J) : USA. Office of Public Health Genomics. Centers for Disease Control and Prevention. Atlanta. GA. ; LITTLE (Julian) : CAN. Department of Epidemiology and Community Medicine. University of Ottawa. Ottawa. ON. ; Cornelia-M VAN DUIJN |[BDSP. Notice produite par INIST-CNRS E9R0xJDp. Diffusion soumise à autorisation]. The rapid and continuing progress in gene discovery for complex diseases is fueling interest in the potential application of genetic risk models for clinical and [...]
Article
Albert HOFMAN ; M. ARFAN IKRAM ; Oscar-H FRANCO ; Harry-La JANSSEN ; Caroline-Cw KLAVER ; Ernst-J KUIPERS ; Tamar-Ec NIJSTEN ; Bruno-Hch STRICKER ; Henning TIEMEIER ; André-G UITTERLINDEN ; Cornelia-M VAN DUIJN ; Meike-W VERNOOIJ ; Jacqueline-Cm WITTEMAN ; Department of Gastroenterology. Erasmus Medical Center. Rotterdam. NLD ; Department of Radiology. Erasmus Medical Center. Rotterdam. NLD |[BDSP. Notice produite par INIST-CNRS Ik79mR0x. Diffusion soumise à autorisation]. The Rotterdam Study is a prospective cohort study ongoing since 1990 in the city of Rotterdam in The Netherlands. The study targets cardiovascular, endocrine, hep[...]
Article
Mcarolina PARDO SILVA ; Behrooz-Z ALIZADEH ; Albert HOFMAN ; Acecile-Jw JANSSENS ; Omer-T NJAJOU ; Cornelia-M VAN DUIJN ; Jacqueline-Cm WITTEMAN ; Department of Epidemiology. Erasmus University Medical Center Rotterdam. Rotterdam. NLD |[BDSP. Notice produite par INIST-CNRS 9JR0xC8C. Diffusion soumise à autorisation]. The purpose of the present study is to examine HFE gene mutations in relation to newly diagnosed (incident) coronary heart disease (CHD). In a population-based fo[...]
Article
Raluca MIHAESCU ; Albert HOFMAN ; Acecile-Jw JANSSENS ; MYRIAM HUNINK (M.G.) : NLD. Department of Radiology. Erasmus Mc. University Medical Center. Rotterdam. ; Eric-Jg SIJBRANDS ; André-G UITTERLINDEN ; Cornelia-M VAN DUIJN ; Mandy VAN HOEK ; Moniek VAN ZITTEREN ; Jacqueline-Cm WITTEMAN ; Department of Epidemiology. Erasmus Mc. University Medical Center. Rotterdam. NLD ; Department of Internal Medicine. Erasmus Mc. University Medical Center. Rotterdam. NLD ; Netherlands Consortium of Healthy Aging. Rotterdam. NLD |[BDSP. Notice produite par INIST-CNRS R0xDp8Do. Diffusion soumise à autorisation]. Reclassification is observed even when there is no or minimal improvement in the area under the receiver operating characteristic curve (AUC), and it is unclear w[...]
Article
Albert HOFMAN ; Monique-Mb BRETELER ; Harry-La JANSSEN ; KRESTIN (Gabriel-P) : NLD. Department of Radiology. Erasmus Medical Center. Rotterdam. ; Ernst-J KUIPERS ; Bruno-Hch STRICKER ; Henning TIEMEIER ; André-G UITTERLINDEN ; Cornelia-M VAN DUIJN ; VINGERLING (Johannes-R) : NLD. Department of Ophthalmology. Erasmus Medical Center. Rotterdam. ; Jacqueline-Cm WITTEMAN |[BDSP. Notice produite par INIST-CNRS kpmBlR0x. Diffusion soumise à autorisation]. The Rotterdam Study is a prospective cohort study ongoing since 1990 in the city of Rotterdam in The Netherlands. The study targets cardiovascular, endocrine, hep[...]
Article
Mcarolina PARDO SILVA ; Albert HOFMAN ; JANSSENS (Acecile-Jw) : NLD. Department of Public Health. Erasmus Mc University Medical Center Rotterdam. Rotterdam. ; Cornelia-M VAN DUIJN ; Jacqueline-Cm WITTEMAN ; Department of Epidemiology & Biostatistics. Erasmus Mc University Medical Center Rotterdam. Rotterdam. NLD |[BDSP. Notice produite par INIST-CNRS R0x7ggRq. Diffusion soumise à autorisation]. Objective To investigate the relationship between the apolipoprotein E (APOE) gene and the risk of mortality in normal weight, overweight and obese individuals. M[...]
Article
Stefania BOCCIA ; Paolo BOFFETTA ; . DONGXIN LIN ; Matthias-Pa EBERT ; Jing-Yuan FANG ; . FANG FANG ZHANG ; Chang-Ming GAO ; Francesco GIANFAGNA ; Tobias GOTZE ; Francesco GRAZIANO ; . HONGBING SHEN ; Rayjean HUNG ; Marina LACASANA-NAVARRO ; Lizbeth LOPEZ-CARRILLO ; You-Lin QIAO ; Gualtiero RICCIARDI ; Rachael STOLZENBERG-SOLOMON ; Emanuela TAIOLI ; Toshiro TAKEZAKI ; Cornelia-M VAN DUIJN ; Yu-Rong WENG ; Department of Epidemiology. Jiangsu Province Institute of Cancer Research. Nanjing. CHN ; Department of Medicine 2. Klinikum rechts der Isar. Technical University of München. München. DEU ; Genetic Epidemiology Cluster. International Agency for Research on Cancer. Lyon. FRA ; Institute of Hygiene. Università Cattolica del Sacro Cuore. Rome. ITA ; Shanghai Institute of Digestive Disease. Shanghai Jiao-Tong University School of Medicine. Shanghai. CHN |[BDSP. Notice produite par INIST-CNRS R0xfq4V7. Diffusion soumise à autorisation]. Methylenetetrahydrofolate reductase (MTHFR) is a key enzyme in the metabolism of folate, whose role in gastric carcinogenesis is controversial. The authors perfor[...]
Article
Vincent-Wv JADDOE ; Albert HOFMAN ; MACKENBACH (Johan-P) : NLD. Department of Public Health. Erasmus Medical Center. Rotterdam. ; Henriëtte-A Moll ; STEEGERS (Eric-Ap) : NLD. Department of Obstetrics & Gynaecology. Erasmus Medical Center. Rotterdam. ; Henning TIEMEIER ; UITTERLINDEN (Andre-G) : NLD. Department of Internal Medicine. Erasmus Medical Center. Rotterdam. ; Albert-J VAN DER HEIJDEN ; Cornelia-M VAN DUIJN ; Frank-C VERHULST |[BDSP. Notice produite par INIST-CNRS 9oGrR0xI. Diffusion soumise à autorisation]. The Generation R Study is a population-based prospective cohort study from fetal life until young adulthood. The study is designed to identify early environmental[...]
Article
Aaron ISAACS ; Yurii-S AULCHENKO ; OOSTRA (Ben-A) : NLD. Department of clinical Genetics. Erasmus Medical Center. Rotterdam. ; Huibert-Ap POLS ; RUTTEN (Wim-Pf) : NLD. Stichting Huisarts Laboratorium. Breda. ; Fakhredin-A SAYED-TABATABAEI ; Anna-Fc SCHUT ; Eric-Jg SIJBRANDS ; Cornelia-M VAN DUIJN ; Jacqueline-Cm WITTEMAN ; Mcarola ZILLIKENS ; Erasmus Medical Center. Department of Internal Medicine. Rotterdam. NLD |[BDSP. Notice produite par INIST-CNRS 0R0x2NUO. Diffusion soumise à autorisation]. Despite considerable progress in unravelling the genetic basis of dyslipidemias, most findings are based on families with extreme phenotypes. We studied lipid lev[...]
Article
Albert HOFMAN ; Monique-Mb BRETELER ; KRESTIN (Gabriel-P) : NLD. Department of Radiology. Erasmus Medical Center. Rotterdam. ; Huibert-A POLS ; Bruno-Hch STRICKER ; Henning TIEMEIER ; André-G UITTERLINDEN ; Cornelia-M VAN DUIJN ; VINGERLING (Johannes-R) : NLD. Department of Ophthalmology. Erasmus Medical Center. Rotterdam. ; Jacqueline-Cm WITTEMAN ; Department of Epidemiology & Biostatistics. Erasmus Medical Center. Rotterdam. NLD ; Department of Internal Medicine. Erasmus Medical Center. Rotterdam. NLD |[BDSP. Notice produite par INIST-CNRS 4Xy3R0xe. Diffusion soumise à autorisation]. The Rotterdam Study is a prospective cohort study ongoing since 1990 in the city of Rotterdam in the Netherlands. The study targets cardiovascular, neurological, [...]
Article
Donald-J LEHMANN ; CORTINA-BORJA (Mario) : GBR. Centre for Paediatric Epidemiology and Biostatistics. Institute of Child Health. University College London. London. ; KEHOE (Patrick-G) : GBR. Care of the Elderly. Department of Clinical Science at North Bristol. University of Bristol. Frenchay Hospital. Bristol. ; PRINCE (Jonathan-A) : SWE. Center for Genomics and Bioinformatics. Karolinska Institute. Stockholm. ; Kristel SLEEGERS ; Adavid Smith ; Cornelia-M VAN DUIJN ; Donald-R WARDEN ; Erasmus Mc. Department of Epidemiology and Biostatistics. Rotterdam. NLD ; University of Oxford. Department of Pharmacology. Oxford Project to Investigate Memory and Ageing. (O.P.T.I.M.A.). Oxford. GBR |[BDSP. Notice produite par INIST-CNRS XWlR0xjG. Diffusion soumise à autorisation]. Apolipoprotein E epsilon4 (APOE*4) is the only fully established susceptibility allele for Alzheimer's disease. One of the most studied candidates is the insertio[...]
