| Titre : | A case-control study of human immunodeficiency virus type 1 seroconversion and risk-related behaviors in the Chicago MACS/CCS Cohort, 1984-1992. (1995) |
| Auteurs : | D.G. OSTROW ; J.S. CHMIEL ; W.J. DIFRANCEISCO ; D.A. WAGSTAFF ; J. WESCH ; Medical coll Wisconsin. Cent Aids intervention res. Dep psychiatry behavioral medicine. Milwaukee WI. USA |
| Type de document : | Article |
| Dans : | American journal of epidemiology (vol. 142, n° 8, 1995) |
| Pagination : | 875-883 |
| Langues: | Anglais |
| Mots-clés : | Virose ; Infection ; Virus ; Epidémiologie ; Facteur risque ; Homme ; Homosexualité ; Bisexualité ; Etats Unis ; Amérique ; Maladie autoimmune ; Sida |
| Résumé : | [BDSP. Notice produite par INIST R0x3Okhw. Diffusion soumise à autorisation]. This paper focuses on 76 human immunodeficiency virus type 1 (HIV-1) seroconverters who concurrently participated in the Chicago, Illinois, component of the Multicenter AIDS Cohort Study (MACS) and the Coping and Change Study (CCS) of homosexual/bisexual men between 1984 and 1992. A nested case-control analysis was performed to assess the critical behavioral risk factors associated with incident HIV-1 infection and the consistency of these relations in early (1984-1988) versus later (1989-1992) phases of the study. Univariate results revealed strong early period associations between seroconversion and various measures of receptive anal intercourse (RAI) that became considerably weaker in the study's later period. The weaker associations reflected the overall decline in levels of RAI among the cohort during the 9 years of observation. In contrast, univariate results revealed stronger later period associations between seroconversion and measures of receptive oral intercourse and insertive anal intercourse. Subsequent multivariate testing did not support the hypothesis that receptive oral intercourse and/or insertive anal intercourse have replaced unprotected RAI as important risk behaviors in the homosexual transmission of HIV-1. |
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