| Titre : | Coronary heart disease prevalence and its relation to risk factors in American Indians : the Strong Heart Study. (1995) |
| Auteurs : | B.V. HOWARD ; L.D. COWAN ; R.R. FABSITZ ; W.J. HOWARD ; E.T. LEE ; A.J. OOPIK ; D.C. Robbins ; P.J. SAVAGE ; T.K. WELTY ; J.L. YEH ; Medlantic res inst. Washington DC. USA |
| Type de document : | Article |
| Dans : | American journal of epidemiology (vol. 142, n° 3, 1995) |
| Pagination : | 254-268 |
| Langues: | Anglais |
| Mots-clés : | Cardiopathie coronaire ; Epidémiologie ; Prévalence ; Homme ; Ethnie ; Facteur risque ; Etats Unis ; Amérique ; Appareil circulatoire [pathologie] |
| Résumé : | [BDSP. Notice produite par INIST 7NtyR0x0. Diffusion soumise à autorisation]. Although coronary heart disease (CHD) is currently the leading cause of death among American Indians, information on the prevalence of CHD and its association with known cardiovascular risk factors is limited. The Strong Heart Study was initiated in 1988 to quantify cardiovascular disease and its risk factors among three geographically diverse groups of American Indians. Members of 13 Indian communities in Arizona, Oklahoma, and South and North Dakota between 45 and 74 years of age underwent a physical examination that included medical history ; an electrocardiogram ; anthropometric and blood pressure measurements ; an oral glucose tolerance test ; and measurements of fasting plasma lipoproteins, fibrinogen, insulin, hemoglobin A1c, and urinary albumin. Prevalence rates of definite myocardial infarction and definite CHD were higher in men than in women at all three centers (p<0.0001) and higher in those with diabetes mellitus (p=0.002 in men and p=0.0003 in women). Diabetes was associated with relatively higher prevalence rates of myocardial infarction (diabetic : nondiabetic prevalence ratio=3.8 vs. 1.9) and CHD (prevalence ratio=4.6 vs. 1.8) in women than in men. Prevalence rates of heart disease were lowest in the communities in Arizona. These findings from the initial Strong Heart Study examination emphasize the importance of diabetes and its associated variables as risk factors for CHD in Native American populations. Am J Epidemiol 1995 ; 142 : 254-68. |
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