| Titre : | Body size and fat distribution as predictors of coronary heart disease among middle-aged and older US men. (1995) |
| Auteurs : | E.B. RIMM ; A. ASCHERIO ; G.A. COLDITZ ; E. GIOVANNUCCI ; D. SPIEGELMAN ; M.J. STAMPFER ; W.C. Willett ; Harvard school public health. Dep epidemiology. Boston MA. USA |
| Type de document : | Article |
| Dans : | American journal of epidemiology (vol. 141, n° 12, 1995) |
| Pagination : | 1117-1127 |
| Langues: | Anglais |
| Mots-clés : | Cardiopathie coronaire ; Epidémiologie ; Personne âgée ; Homme ; Obésité ; Facteur risque ; Etats Unis ; Amérique ; Etude prospective ; Appareil circulatoire [pathologie] |
| Résumé : | [BDSP. Notice produite par INIST R0xOivmo. Diffusion soumise à autorisation]. Obesity, android fat distribution, and other anthropometric measures have been associated with coronary heart disease in long-term prospective studies. However, fluctuations in weight due to age-related hormonal changes and changes in lifestyle practices may bias relative risk estimates over a long follow-up period. The authors prospectively studied the association between body mass index (BMI) (kg/m2), waist-to-hip ratio, and height as independent predictors of incident coronary heart disease in a 3-year prospective study among 29,122 US men aged 40-75 years in 1986. The authors documented 420 incident coronary events during the follow-up period. Among men younger than 65, after adjusting for other coronary risk factors, the relative risk was 1.72 (95% confidence interval (Cl) 1.102.69) for men with BMI of 25-28.9,2.61 (95% Cl 1.54-4.42) for BMI of 29.0-32.9, and 3.44 (95% Cl 1.67-7.09) for obese men with BMI 33 compared with lean men with BMI<23.0. Among men<65 years of age, the association between BMI and risk of coronary heart disease was much weaker. However, in this age group, the waist-to-hip ratio was a much stronger predictor of risk. These results suggest that for younger men, obesity, independent of fat distribution, is a strong risk factor for coronary heart disease. For older men, measures of fat distribution may be better than body mass index at predicting risk of coronary disease. An J Epidemiol 1995 ; 141 : 1117-27. |
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