No association between serum ferritin and asymptom... Catalogue en ligne

Titre :	No association between serum ferritin and asymptomatic carotid atherosclerosis : the atherosclerosis risk in communities (ARIC) study. (1995)
Auteurs :	M. MOORE ; R.W. BARNES ; J.H. ECKFELDT ; A.R. FOLSOM
Type de document :	Article
Dans :	American journal of epidemiology (vol. 141, n° 8, 1995)
Pagination :	719-723
Langues:	Anglais
Mots-clés :	Artériosclérose ; Homme ; Epidémiologie ; Ferritine ; Fer ; Etiologie ; Etats Unis ; Amérique ; Appareil circulatoire [pathologie]
Résumé :	[BDSP. Notice produite par INIST bkR0xcQ3. Diffusion soumise à autorisation]. A possible association between body iron stores, measured as serum ferritin, and carotid arterial intima-media thickening was investigated in the Atherosclerosis Risk in Communities Study during 1990-1992 using a matched case-control design. For a 143-mug/liter greater serum ferritin concentration (the interquartile range), the odds ratio for cases with carotid intima-media thickening versus controls was 1.12 (95% confidence interval 0.97-1.30). However, there was no association (odds ratio=1.00) after adjusting for major cardiovascular risk factors. This analysis of carotid arterial intima-media thickening, a measure of early atherosclerosis, in relation to serum ferritin does not support the hypothesis that increased body iron stores increase the risk of atherosclerotic cardiovascular disease.

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