| Titre : | Leukemia, brain tumors, and exposure to extremely low frequency electromagnetic fields in Swiss railway employees. (2001) |
| Auteurs : | C.E. MINDER ; D.H. PFLUGER ; Institute for Social and Preventive Medicine. University of Berne. Berne. CHE |
| Type de document : | Article |
| Dans : | American journal of epidemiology (vol. 153, n° 9, 2001) |
| Pagination : | 825-835 |
| Langues: | Anglais |
| Mots-clés : | Leucémie ; Cancer ; Exposition professionnelle ; Magnétisme ; Epidémiologie ; Facteur risque ; Homme ; Suisse ; Europe ; Médecine travail ; Système nerveux [pathologie] |
| Résumé : | [BDSP. Notice produite par INIST 556SR0xQ. Diffusion soumise à autorisation]. Railway engineers provide excellent opportunities for studying the relation between exposure to extremely low frequency magnetic fields and leukemia or brain tumors. In a cohort study of Swiss railway personnel with 2.7 x 105 person-years of follow-up (1972-1993), the authors compared occupations with high average exposures (line engineers : 25.9 muT) to those with medium and low exposures (station masters : 1 muT). The mortality rate ratio for leukemia was 2.4 (95% confidence interval (Cl) : 1.0,6.1) among line engineers (reference category : station masters). The mortality rate ratio for brain tumors was 1.0 (95% Cl : 0.2,4.6) among line engineers and 5.1 (95% Cl : 1.2,21.2) among shunting yard engineers (compared with station masters). Two exposure characteristics were evaluated : cumulative exposure in muT-years and years spent under exposure to magnetic fields of >=10 muT. There was a significant increase in leukemia mortality of 0.9% (95% Cl : 0.2,1.7) per muT-year of cumulative exposure to extremely low frequency magnetic fields. The increase by years spent under exposure of >=10 muT was even stronger : 62% per year (95% Cl : 15,129). Brain cancer risk did not show a dose-response relation. This study contributes to the evidence for a link between heavy exposure to extremely low frequency magnetic fields and leukemia. Its strengths include reliable measurements and reliable historical reconstruction of exposures. |
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