Titre :
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Time trends in autism and in MMR immunization coverage in California. (2001)
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Auteurs :
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Loring DALES ;
Sandra-Jo HAMMER ;
Natalie-J Smith ;
Immunization Branch. California Department of Health Services. Berkeley. USA
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Type de document :
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Article
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Dans :
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JAMA - Journal of the american medical association (vol. 285, n° 9, 2001)
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Pagination :
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1183-1185
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Langues:
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Anglais
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Mots-clés :
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Autisme
;
Vaccin
;
Virus
;
Etats Unis
;
Amérique
;
Epidémiologie
;
Evolution
;
Etiologie
;
Enfant
;
Homme
;
Trouble développement
;
Amérique du Nord
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Résumé :
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[BDSP. Notice produite par INIST 1TnG1R0x. Diffusion soumise à autorisation]. Context Considerable concern has been generated in the lay and medical communities by a theory that increased measles-mumps-rubella (MMR) immunization among young children may be the cause of an apparent marked increase in autism occurrence. Objective To determine if a correlation exists in secular trends of MMR immunization coverage among young children and autism occurrence. Design, Setting, and Participants Retrospective analyses of MMR immunization coverage rates among children born in 1980-1994 who were enrolled in California kindergartens (survey samples of 600-1900 children each year) and whose school immunization records were reviewed to retrospectively determine the age at which they first received MMR immunization ; and of autism caseloads among children born in these years who were diagnosed with autism and were enrolled in the California Department of Developmental Services regional service center system. Main Outcome Measures Measles-mumps-rubella immunization coverage rates as of ages 17 months and 24 months and numbers of Department of Developmental Services system enrollees diagnosed with autism, grouped by year of birth. Results Essentially no correlation was observed between the secular trend of early childhood MMR immunization rates in California and the secular trend in numbers of children with autism enrolled in California's regional service center system. (...)
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