| Titre : | Body size at birth and blood pressure among children in developing countries. Commentary : Fetal origins of health and disease. (2001) |
| Auteurs : | C.M. LAW ; D.J.P. BARKER ; O. DADA ; H. DELGADO ; P. EGGER ; E. KYLBERG ; P. LAVIN ; A.W. SHIELL ; G.H. TANG ; H. VON HERTZEN ; C.S. YAJNIK ; Mrc Environmental Epidemiology Unit. Southampton General Hospital. Southampton. GBR |
| Type de document : | Article |
| Dans : | International journal of epidemiology (vol. 30, n° 1, 2001) |
| Pagination : | 52-59 |
| Langues: | Anglais |
| Mots-clés : | Taille corporelle ; Naissance ; Grossesse ; Pays voie développement ; Facteur risque ; Enfant ; Homme ; Epidémiologie ; Foetopathie ; Gestation [pathologie] |
| Résumé : | [BDSP. Notice produite par INIST fNJylR0x. Diffusion soumise à autorisation]. Background Studies in developed countries have shown that reduced fetal growth is related to raised blood pressure in childhood and adult life. Little is known about this association in developing countries, where fetal growth retardation is common. Methods In 1994-1995, we measured blood pressure in 1570 3-6-year-old children living in China, Guatemala, Chile, Nigeria and Sweden. We related their blood pressure to patterns of fetal growth, as measured by body proportions at birth. The children were all born after 37 weeks gestation and weighed more than 2.5 kg at birth. Results In each country, blood pressure was positively related to the child's current weight. After adjusting for this and gender, systolic pressure was inversely related to size at birth in all countries except Nigeria. In Chile, China and Guatemala, children who were proportionately small at birth had raised systolic pressure. For example, in Chile, systolic pressure adjusted for current weight increased by 4.9 mmHg (95% CI : 2.1,7.7) for every kilogram decrease in birthweight, by 1 mmHg (95% CI : 0.4,1.6) for every centimetre decrease in birth length, and by 1.3 mmHg (95% CI : 0.4,2.2) for every centimetre decrease in head circumference at birth. In Sweden, systolic pressure was higher in children who were disproportionately small, that is thin, at birth. Systolic pressure increased by 0.3 mmHg (95% CI : 0.0,0.6) for every unit (kg/m3) decrease in ponderal index at birth. (...) |
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