| Titre : | Uterine fibroids. (2001) |
| Auteurs : | Elizabeth-A STEWART |
| Type de document : | Article |
| Dans : | Lancet (The) (vol. 357, n° 9252, 2001) |
| Pagination : | 293-298 |
| Langues: | Anglais |
| Mots-clés : | Utérus ; Symptôme ; Diagnostic ; Epidémiologie ; Thérapeutique ; Thérapeutique médicamenteuse ; Chirurgie ; Femme ; Adulte ; Homme ; Tumeur bénigne ; Utérus [pathologie] |
| Résumé : | [BDSP. Notice produite par INIST 3jR0x0ht. Diffusion soumise à autorisation]. Uterine lelomyomas (fibroids or myomas), benign tumours of the human uterus, are the single most common indication for hysterectomy. They are clinically apparent In up to 25% of women and cause significant morbidity, Including prolonged or heavy menstrual bleeding, pelvic pressure or pain, and, In rare cases, reproductive dysfunction. Thus, both the economic cost and the effect on quality of life are substantial. Surgery has been the mainstay of fibroid treatment, and various minimally Invasive procedures have been developed In addition to hysterectomy and abdominal myomectomy. Formation of new lelomyomas after these conservative therapies remains a substantial problem. Although medications that manipulate concentrations of steroid hormones are effective, side-effects limit long-term use. A better approach may be manipulation of the steroid-hormone environment with specific hormone antagonists. There has been little evidence-based evaluation of therapy. New research Into the basic biology of these neoplasms may add new treatment options for the future as the role of growth factors and genetic mutations In these tumours are better understood. |
Service Documentation EHESP
Me connecter
PORTAIL DOCUMENTAIRE
École des hautes études en santé publique
Catalogue
Multi-bases
Accueil
Sélection de la langue
Adresse
Service Documentation EHESPBibliothèque Rennes Avenue du Professeur Léon Bernard – CS 74312 – 35043 Rennes Cedex Bibliothèque MSSH Paris 20 avenue George Sand - 93210 La Plaine Saint-Denis
France
Bibliothèque Rennes : 02 99 02 29 50 Bibliothèque MSSH Paris : 02 99 02 24 50
contact